Using ultrahigh-frequency ultrasound to detect small lung nodules
Official title: The Value of Ultrahigh-frequency Ultrasonography (UHFUS) in Detection of Small Pulmonary Ground Glass Opacity (GGO) in Vitro: A Prospective Pilot Study
Run by Peking Union Medical College Hospital · NCT05994898 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new ultrasound method to see if it can help doctors find small lung nodules more effectively in patients who have had lung tissue removed.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Peking Union Medical College Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT05994898 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with targeted lung nodules that require surgical removal and who are undergoing video-assisted thoracoscopic surgery (VATS) or robotic-assisted thoracoscopic surgery (RATS).
✕Probably not a fit
Patients who refuse enrollment or have pulmonary nodules labeled during the operation may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the feasibility of ultrahigh-frequency ultrasound (UHFUS) for detecting ground glass opacities (GGOs) in excised lung tissue. It involves a sequential approach where GGOs are identified through palpation, UHFUS, and open biopsy, with a focus on comparing detection rates and time efficiency. The study also employs Bland-Altman analysis to assess the agreement between tumor sizes measured by CT, UHFUS, and pathology. The aim is to improve the detection of GGOs, which are critical for lung cancer diagnosis and treatment.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of GGO detection, leading to better surgical outcomes for lung cancer patients.
How similar studies have gone: While the use of UHFUS for GGO detection is a novel approach, similar imaging techniques have shown promise in improving detection rates in other contexts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with targeted nodules identified as lesions required surgical removed such as main lesion and high-risk nodules; 2. Patients who accept VATS or RATS resection. Exclusion Criteria: 1. Patients refused enrollment in the trial; 2. Pulmonary nodules were labelled during the operation.
Where it's running
-
Department of thoracic surgery
Beijing, Beijing, China Recruiting
Study contacts
- Principal investigator: Shanqing Li, Prof. — Peking Union Medical College Hospital
- Study coordinator: Xuehan Gao, MD
- Email: gaoxh1299@163.com
- Phone: +86 18801341299
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.