Clinical trial No longer in our active list Observational

Using ultrahigh-frequency ultrasound to detect small lung nodules

Official title: The Value of Ultrahigh-frequency Ultrasonography (UHFUS) in Detection of Small Pulmonary Ground Glass Opacity (GGO) in Vitro: A Prospective Pilot Study

Run by Peking Union Medical College Hospital · NCT05994898 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing a new ultrasound method to see if it can help doctors find small lung nodules more effectively in patients who have had lung tissue removed.

Quick facts

Study typeObservational
SexAll
Enrollment50 (estimated)
SponsorPeking Union Medical College Hospital
Academic / other
Locations1 site (Beijing, Beijing)
Trial IDNCT05994898 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with targeted lung nodules that require surgical removal and who are undergoing video-assisted thoracoscopic surgery (VATS) or robotic-assisted thoracoscopic surgery (RATS).

Probably not a fit

Patients who refuse enrollment or have pulmonary nodules labeled during the operation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the feasibility of ultrahigh-frequency ultrasound (UHFUS) for detecting ground glass opacities (GGOs) in excised lung tissue. It involves a sequential approach where GGOs are identified through palpation, UHFUS, and open biopsy, with a focus on comparing detection rates and time efficiency. The study also employs Bland-Altman analysis to assess the agreement between tumor sizes measured by CT, UHFUS, and pathology. The aim is to improve the detection of GGOs, which are critical for lung cancer diagnosis and treatment.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of GGO detection, leading to better surgical outcomes for lung cancer patients.

How similar studies have gone: While the use of UHFUS for GGO detection is a novel approach, similar imaging techniques have shown promise in improving detection rates in other contexts.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients with targeted nodules identified as lesions required surgical removed such as main lesion and high-risk nodules;
2. Patients who accept VATS or RATS resection.

Exclusion Criteria:

1. Patients refused enrollment in the trial;
2. Pulmonary nodules were labelled during the operation.

Where it's running

  • Department of thoracic surgery
    Beijing, Beijing, China
    Recruiting

Study contacts

  • Principal investigator: Shanqing Li, Prof. — Peking Union Medical College Hospital
  • Study coordinator: Xuehan Gao, MD
  • Email: gaoxh1299@163.com
  • Phone: +86 18801341299

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.