Using turmeric to manage thumb arthritis pain
Official title: A Randomized Controlled Trial Using Turmeric for Patients With Basal Joint Arthritis
Run by Massachusetts General Hospital · NCT03017118 · Data updated 2026-11-12
This study is testing if turmeric can help people with thumb arthritis feel less pain and stiffness compared to a placebo.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | August 9, 2017 |
| Main results expected | December 2027 |
| Study ends | January 2028 |
| Registry record updated | November 24, 2025 |
| Trial ID | NCT03017118 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 40 and older who are experiencing basal joint pain and have specific radiographic evidence of early-stage arthritis.
✕Probably not a fit
Patients with advanced basal joint arthritis, inflammatory disorders, or those currently receiving other treatments for their condition may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of turmeric, a nutraceutical, in managing pain and stiffness in patients suffering from basal joint arthritis, specifically thumb osteoarthritis. It is designed as a pilot randomized controlled trial, comparing the effects of turmeric against a placebo. Participants will be assessed for their symptoms and radiographic evidence of the condition to determine the impact of turmeric on their arthritis management.
Why it matters
Potential benefit: If successful, this study could provide a natural and effective option for patients to alleviate pain and improve function in thumb osteoarthritis.
How similar studies have gone: While the use of turmeric in arthritis management is gaining interest, this specific approach is relatively novel and has not been extensively tested in similar studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 40 years of age or older * English fluency and literacy * Seeking care for basal joint pain * Tender over basal joint * Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction) * Radiographic evidence of Eaton stage 1 and 2 only Exclusion Criteria: * Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment * Inability or unwillingness to participate in a trial study * Rheumatoid Arthritis or other inflammatory disorder diagnoses * Post-traumatic osteoarthritis * Patients on Coumadin/Steroids/NSAIDs/Tylenol * Diabetes Mellitus * Pregnant or lactating women * Basal joint arthritis of Eaton stage 3 * Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)
Where it's running
-
Massachusetts General Hospital
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Neal Chen, MD — Massachusetts General Hospital
- Study coordinator: Neal Chen, M.D.
- Email: nchen1@mgh.harvard.edu
- Phone: 617-726-4700
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Thumb base arthritis: joint replacement vs trapeziectomy
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This observational study tests a biopsychosocial assessment for people with trapeziometacarpal osteoarthritis and uses AI to help predict patient profiles.
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Comparing NSAID and corticosteroid injections for thumb arthritis treatment
This study is testing whether a pain-relieving injection with ketorolac or a corticosteroid injection with triamcinolone works better for people with thumb arthritis who haven't found relief from other treatments.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.