Clinical trial Recruiting at 1 site Interventional Ages 40 and up

Using turmeric to manage thumb arthritis pain

Official title: A Randomized Controlled Trial Using Turmeric for Patients With Basal Joint Arthritis

Run by Massachusetts General Hospital · NCT03017118 · Data updated 2026-11-12

This study is testing if turmeric can help people with thumb arthritis feel less pain and stiffness compared to a placebo.

Quick facts

Study typeInterventional
Ages40 Years and up
SexAll
Enrollment60 (estimated)
SponsorMassachusetts General Hospital
Academic / other
Locations1 site (Boston, Massachusetts)
StatusRecruiting
StartedAugust 9, 2017
Main results expectedDecember 2027
Study endsJanuary 2028
Registry record updatedNovember 24, 2025
Trial IDNCT03017118 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 40 and older who are experiencing basal joint pain and have specific radiographic evidence of early-stage arthritis.

Probably not a fit

Patients with advanced basal joint arthritis, inflammatory disorders, or those currently receiving other treatments for their condition may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of turmeric, a nutraceutical, in managing pain and stiffness in patients suffering from basal joint arthritis, specifically thumb osteoarthritis. It is designed as a pilot randomized controlled trial, comparing the effects of turmeric against a placebo. Participants will be assessed for their symptoms and radiographic evidence of the condition to determine the impact of turmeric on their arthritis management.

Why it matters

Potential benefit: If successful, this study could provide a natural and effective option for patients to alleviate pain and improve function in thumb osteoarthritis.

How similar studies have gone: While the use of turmeric in arthritis management is gaining interest, this specific approach is relatively novel and has not been extensively tested in similar studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 40 years of age or older
* English fluency and literacy
* Seeking care for basal joint pain
* Tender over basal joint
* Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction)
* Radiographic evidence of Eaton stage 1 and 2 only

Exclusion Criteria:

* Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment
* Inability or unwillingness to participate in a trial study
* Rheumatoid Arthritis or other inflammatory disorder diagnoses
* Post-traumatic osteoarthritis
* Patients on Coumadin/Steroids/NSAIDs/Tylenol
* Diabetes Mellitus
* Pregnant or lactating women
* Basal joint arthritis of Eaton stage 3
* Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)

Where it's running

  • Massachusetts General Hospital
    Boston, Massachusetts, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.