Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using transthoracic echocardiography to improve care for stable chest pain

Official title: Improving the Clinical Management of Stable Chest Pain Based on Imaging: a Registry of Transthorcic Echocardiography

Run by Tianjin Chest Hospital · NCT07063147 · Data updated 2026-11-12

This project will test whether adding transthoracic echocardiography (TTE) helps doctors make better decisions and lowers major heart problems in adults with stable chest pain suspected to be from coronary artery disease.

More Coronary Artery Disease trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50000 (estimated)
SponsorTianjin Chest Hospital
Academic / other
Locations1 site (Tianjin)
StatusRecruiting
StartedJanuary 1, 2025
Main results expectedDecember 31, 2030
Study endsDecember 31, 2040
Registry record updatedJuly 18, 2025
Trial IDNCT07063147 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) with symptomatic stable chest pain referred for TTE because their doctors suspect obstructive coronary artery disease, who can give informed consent and do not have prior coronary disease or other excluded cardiac conditions.

Probably not a fit

People with acute coronary syndromes, prior coronary disease or revascularization, non-sinus rhythm, cardiomyopathy, significant valvular or congenital heart disease, or heart failure from other causes are excluded and would not be expected to benefit from this TTE-based approach in this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study enrolling adults referred for TTE to evaluate stable chest pain suspected of obstructive coronary artery disease. All participants receive TTE performed according to guidelines and local protocols, and their subsequent clinical decisions and outcomes are tracked. The study will compare rates of major adverse cardiac events (MACE) and the use of downstream tests and interventions among patients managed with TTE information. Findings will show whether TTE-based imaging contributes meaningful additional information for clinical management.

Why it matters

Potential benefit: If successful, using TTE could reduce major adverse cardiac events and decrease unnecessary invasive tests by improving diagnostic and treatment decisions for people with stable chest pain.

How similar studies have gone: Transthoracic echocardiography is well established for assessing cardiac structure and function, but using routine TTE specifically to guide management of stable chest pain is relatively novel and has limited direct evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* symptomatic patients with SCP suspected of obstructive CAD.
* referred for TTE for the assessment of SCP.
* ≥18 years of age.
* signed informed consent.

Exclusion Criteria:

* acute coronary syndromes
* previous CAD or coronary revascularization
* nonsinus rhythm
* cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons

Where it's running

  • Tianjin Chest Hospital
    Tianjin, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.