Using transthoracic echocardiography to improve care for stable chest pain
Official title: Improving the Clinical Management of Stable Chest Pain Based on Imaging: a Registry of Transthorcic Echocardiography
Run by Tianjin Chest Hospital · NCT07063147 · Data updated 2026-11-12
This project will test whether adding transthoracic echocardiography (TTE) helps doctors make better decisions and lowers major heart problems in adults with stable chest pain suspected to be from coronary artery disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50000 (estimated) |
| Sponsor | Tianjin Chest Hospital Academic / other |
| Locations | 1 site (Tianjin) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2040 |
| Registry record updated | July 18, 2025 |
| Trial ID | NCT07063147 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) with symptomatic stable chest pain referred for TTE because their doctors suspect obstructive coronary artery disease, who can give informed consent and do not have prior coronary disease or other excluded cardiac conditions.
✕Probably not a fit
People with acute coronary syndromes, prior coronary disease or revascularization, non-sinus rhythm, cardiomyopathy, significant valvular or congenital heart disease, or heart failure from other causes are excluded and would not be expected to benefit from this TTE-based approach in this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective observational study enrolling adults referred for TTE to evaluate stable chest pain suspected of obstructive coronary artery disease. All participants receive TTE performed according to guidelines and local protocols, and their subsequent clinical decisions and outcomes are tracked. The study will compare rates of major adverse cardiac events (MACE) and the use of downstream tests and interventions among patients managed with TTE information. Findings will show whether TTE-based imaging contributes meaningful additional information for clinical management.
Why it matters
Potential benefit: If successful, using TTE could reduce major adverse cardiac events and decrease unnecessary invasive tests by improving diagnostic and treatment decisions for people with stable chest pain.
How similar studies have gone: Transthoracic echocardiography is well established for assessing cardiac structure and function, but using routine TTE specifically to guide management of stable chest pain is relatively novel and has limited direct evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * symptomatic patients with SCP suspected of obstructive CAD. * referred for TTE for the assessment of SCP. * ≥18 years of age. * signed informed consent. Exclusion Criteria: * acute coronary syndromes * previous CAD or coronary revascularization * nonsinus rhythm * cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons
Where it's running
-
Tianjin Chest Hospital
Tianjin, China Recruiting
Study contacts
- Study coordinator: Jia Zhou
- Email: zhoujiawenzhang@126.com
- Phone: +8615522485560
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Effects of Tirzepatide on Heart Health in Overweight Individuals
This study tests if tirzepatide can improve heart health and reduce plaque in the arteries of overweight people with stable coronary artery disease.
-
Evaluating aspirin's effectiveness in patients with chronic coronary syndromes who can't undergo revascularization
This study is testing whether aspirin can help people with chronic coronary syndromes who can't have surgery to improve their heart health.
-
Using CCTA to improve management of stable chest pain
This study is testing if using a special heart scan called CCTA can help doctors better manage stable chest pain and reduce serious heart problems for patients suspected of having blocked arteries.
-
μFR-guided Drug-Coated Balloon Angioplasty vs Angiography-guided Angioplasty in Coronary Artery Disease
This trial tests whether using computational μFR guidance during drug-coated balloon angioplasty is better than standard angiography guidance for people with de novo coronary artery lesions.
-
Gastric Ultrasound Before CABG to See if Heart Function Changes Stomach Contents
This study checks whether people with weaker heart function before elective CABG have different stomach contents seen on ultrasound.
-
Can preoperative photon-counting CT help predict heart recovery after bypass surgery?
This observational study tests whether a preoperative photon-counting CT can help predict heart function 3 months after coronary bypass surgery in adults with coronary artery disease.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.