Clinical trial Recruiting at 5 sites Observational Ages 18 to 100

Using transesophageal echocardiography to diagnose blunt traumatic aortic injury

Official title: Emergency Physician Performed Transesophageal Echocardiography To Diagnose Blunt Traumatic Aortic Injury

Run by Hospital Raja Permaisuri Bainun · NCT05226858 · Data updated 2026-11-12

This study is testing if a special heart ultrasound done by emergency doctors can help quickly diagnose serious aortic injuries in patients with chest trauma.

More Chest Trauma trials

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment56 (estimated)
SponsorHospital Raja Permaisuri Bainun
Government
Locations6 sites (Alor Star, Kedah and 5 other locations)
StatusRecruiting
StartedMarch 15, 2022
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedMarch 13, 2025
Trial IDNCT05226858 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are trauma patients in the emergency department with suspected blunt traumatic aortic injury.

Probably not a fit

Patients under 18 years old or those with contraindications to transesophageal echocardiography, such as suspected esophageal injury, will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter observational trial aims to evaluate the effectiveness of transesophageal echocardiography (TEE) performed by emergency physicians in diagnosing blunt traumatic aortic injury (BTAI) in patients with chest trauma. All patients suspected of having BTAI will undergo TEE as part of their emergency care, with findings compared to computed tomography angiography (CTA), which serves as the reference standard. The study also assesses the hemodynamic status and cardiac function of patients through TEE, providing a comprehensive evaluation of their condition. Informed consent will be obtained from patients or their next of kin prior to the procedure.

Why it matters

Potential benefit: If successful, this approach could lead to faster and more accurate diagnosis of blunt traumatic aortic injuries, improving patient outcomes in emergency settings.

How similar studies have gone: While the use of TEE in trauma settings is established, this specific application for diagnosing BTAI is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

All trauma patients with suspected BTAI in the emergency department (ED) who undergo both TEE and CTA.

Exclusion Criteria:

1. Children (age under 18 years) will not be eligible for inclusion in this study.
2. Patients with contraindication to TEE such as suspected esophageal injury or pathology

Where it's running

  • Hospital Sultanah Bahiyah
    Alor Star, Kedah, Malaysia
    Recruiting
  • Hospital Raja Permaisuri Bainun
    Ipoh, Perak, Malaysia
    Recruiting
  • Hospital Kuala Lumpur
    Kuala Lumpur, Malaysia
    Recruiting
  • University of Malaya
    Kuala Lumpur, Malaysia
    Recruiting
  • Hospital Melaka
    Malacca, Malaysia
    Recruiting
  • Hospital Queen Elizabeth
    Kota Kinabalu, Sabah, Malaysia
    Terminated

Study contacts

  • Principal investigator: Adi Osman, MD — Hospital Raja Permaisuri Bainun
  • Study coordinator: Adi Osman, MD
  • Email: osman.adi@gmail.com
  • Phone: +6052087006

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.