Using transesophageal echocardiography to diagnose blunt traumatic aortic injury
Official title: Emergency Physician Performed Transesophageal Echocardiography To Diagnose Blunt Traumatic Aortic Injury
Run by Hospital Raja Permaisuri Bainun · NCT05226858 · Data updated 2026-11-12
This study is testing if a special heart ultrasound done by emergency doctors can help quickly diagnose serious aortic injuries in patients with chest trauma.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 56 (estimated) |
| Sponsor | Hospital Raja Permaisuri Bainun Government |
| Locations | 6 sites (Alor Star, Kedah and 5 other locations) |
| Status | Recruiting |
| Started | March 15, 2022 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | March 13, 2025 |
| Trial ID | NCT05226858 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are trauma patients in the emergency department with suspected blunt traumatic aortic injury.
✕Probably not a fit
Patients under 18 years old or those with contraindications to transesophageal echocardiography, such as suspected esophageal injury, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter observational trial aims to evaluate the effectiveness of transesophageal echocardiography (TEE) performed by emergency physicians in diagnosing blunt traumatic aortic injury (BTAI) in patients with chest trauma. All patients suspected of having BTAI will undergo TEE as part of their emergency care, with findings compared to computed tomography angiography (CTA), which serves as the reference standard. The study also assesses the hemodynamic status and cardiac function of patients through TEE, providing a comprehensive evaluation of their condition. Informed consent will be obtained from patients or their next of kin prior to the procedure.
Why it matters
Potential benefit: If successful, this approach could lead to faster and more accurate diagnosis of blunt traumatic aortic injuries, improving patient outcomes in emergency settings.
How similar studies have gone: While the use of TEE in trauma settings is established, this specific application for diagnosing BTAI is novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: All trauma patients with suspected BTAI in the emergency department (ED) who undergo both TEE and CTA. Exclusion Criteria: 1. Children (age under 18 years) will not be eligible for inclusion in this study. 2. Patients with contraindication to TEE such as suspected esophageal injury or pathology
Where it's running
-
Hospital Sultanah Bahiyah
Alor Star, Kedah, Malaysia Recruiting -
Hospital Raja Permaisuri Bainun
Ipoh, Perak, Malaysia Recruiting -
Hospital Kuala Lumpur
Kuala Lumpur, Malaysia Recruiting -
University of Malaya
Kuala Lumpur, Malaysia Recruiting -
Hospital Melaka
Malacca, Malaysia Recruiting -
Hospital Queen Elizabeth
Kota Kinabalu, Sabah, Malaysia Terminated
Study contacts
- Principal investigator: Adi Osman, MD — Hospital Raja Permaisuri Bainun
- Study coordinator: Adi Osman, MD
- Email: osman.adi@gmail.com
- Phone: +6052087006
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.