Using Tranexamic Acid to Reduce Blood Loss in Pediatric Hip Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of tranexamic acid (TXA), an antifibrinolytic agent, in reducing intraoperative blood loss and the need for blood transfusions in pediatric patients undergoing proximal femoral and acetabular osteotomies. The trial compares outcomes between patients receiving TXA and those receiving a placebo. By promoting hemostasis and preventing fibrin degradation, TXA aims to improve surgical outcomes in this vulnerable population. The study is designed to fill the gap in existing literature regarding the safety and efficacy of TXA in pediatric orthopedic procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ASA I - II
* Scheduled for acetabular osteotomy and/or proximal femoral derotation osteotomies.

Exclusion Criteria:

* Patient's guardian refusal to participate in the study.
* Children known to have pre-existing bleeding or coagulation disorders.
* Children with anemia; defined according to (WHO ) cutoffs as Hb level\<11g/dl for girls and \<12g/dl for boys
* History of epilepsy.
* History of renal insufficiency or failure

Where it's running

• Assiut University
  Asyut, Egypt Recruiting

Study contacts

• Study coordinator: Shimaa A Hassan, M.D.
• Email: shimaa.abbas@med.aun.edu.eg
• Phone: 01002953253

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.