Using Tranexamic Acid to Reduce Blood Loss in Hip Replacement Surgery
Utilisation of Tranexamic Acid in Elective Hip Arthroplasty
St. Anne's University Hospital Brno, Czech Republic · NCT06903299
This study is testing if using tranexamic acid during hip replacement surgery can help reduce blood loss and the need for blood transfusions in patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Sex | All |
| Sponsor | St. Anne's University Hospital Brno, Czech Republic (other) |
| Locations | 1 site (Brno, Czechia) |
| Trial ID | NCT06903299 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of tranexamic acid (TXA), an antifibrinolytic agent, in patients undergoing elective hip arthroplasty to reduce perioperative blood loss. TXA works by inhibiting the activation of plasminogen, thereby decreasing bleeding during and after surgery. The study aims to assess the effectiveness of intra-articular application of TXA in minimizing the need for blood transfusions and managing hemoglobin changes post-surgery. It focuses on patients who are scheduled for elective hip replacements, excluding those with traumatic indications.
Who should consider this trial
Good fit: Ideal candidates for this study are patients scheduled for elective hip replacement surgery.
Not a fit: Patients requiring hip replacement due to traumatic injuries will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce blood loss and the need for blood transfusions in patients undergoing hip replacement surgery.
How similar studies have performed: Previous studies have shown promising results with the use of tranexamic acid in reducing blood loss in orthopedic surgeries, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Elective hip replacement Exclusion Criteria: * Traumatic hip replacement indication
Where this trial is running
Brno, Czechia
- First Department of Orthopaedic Surgery, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czechia — Brno, Czechia, Czech Republic (RECRUITING)
Study contacts
- Study coordinator: Pavel Brančík
- Email: pavel.brancik@fnusa.cz
- Phone: +420 728 356 094
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Blood Loss, Hemoglobin Change, Blood Transfusion, Heterotopic Ossification