Using tranexamic acid to reduce blood loss in hip fracture surgeries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of tranexamic acid (TXA) in reducing postoperative blood loss in adults with hip fractures undergoing surgical fixation. The study is conducted at a Level II trauma center and involves administering TXA intravenously before incision and at wound closure. By assessing blood loss in both intracapsular and extracapsular hip fractures, the trial aims to establish a standard dosing pattern that could improve patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. All adult (18 years old or older) hip fracture patients presenting with an acute hip fracture and undergoing operative fixation

Exclusion Criteria:

1. Polytrauma patients
2. Previous operation on the ipsilateral hip
3. Patients with coagulopathies (Factor V Leiden, Sickle Cell Anemia, Etc.)
4. Patients with \< 6-month history of thromboembolic event (DVT/PE), Stroke, Cardiac Stents, or Myocardial Infarction (MI)
5. History of seizure disorder
6. Patients on birth control
7. Pregnant Women
8. Prisoners
9. Active thromboembolic disease (DVT/PE, MI, Stroke)

Where it's running

• Ascension Genesys Hospital
  Grand Blanc, Michigan, United States Recruiting

Study contacts

• Study coordinator: Jacob Hinkley, DO, MS
• Email: jacob.hinkley2@ascension.org
• Phone: 810-606-5669

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.