Using tranexamic acid to reduce blood loss during vaginal hysterectomy
Official title: Local Tranexamic Acid During Vaginal Hysterectomy to Reduce Blood Loss
Run by Meir Medical Center · NCT04760301 · Data updated 2026-11-12
This study is testing if a local injection of tranexamic acid can help reduce blood loss during vaginal hysterectomy surgeries.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 90 Years |
| Sex | Women only |
| Enrollment | 60 (estimated) |
| Sponsor | Meir Medical Center Academic / other |
| Locations | 2 sites (Kfar Saba, Israel and 1 other locations) |
| Status | Recruiting |
| Started | February 16, 2021 |
| Main results expected | July 2025 |
| Study ends | June 2026 |
| Registry record updated | May 6, 2025 |
| Trial ID | NCT04760301 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are female patients aged 20-90 who are scheduled for a vaginal hysterectomy.
✕Probably not a fit
Patients experiencing massive bleeding due to major vessel injury or those with known coagulopathies or sensitivity to tranexamic acid may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to evaluate the effectiveness of local tranexamic acid in minimizing blood loss during vaginal hysterectomy procedures. Participants will be randomly assigned to receive either a local injection of tranexamic acid or a placebo (saline) at the start of the surgery. The study will measure the amount of blood loss during the operation to determine if tranexamic acid can significantly reduce bleeding. This approach could provide a simple and effective method to enhance surgical outcomes for patients undergoing this procedure.
Why it matters
Potential benefit: If successful, this treatment could lead to reduced blood loss during vaginal hysterectomies, improving patient safety and recovery.
How similar studies have gone: Other studies have shown promising results with the use of tranexamic acid in surgical settings, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 20-90 years old female patients going through vaginal hysterctomy Exclusion Criteria: * massive bleeding during operation due to major vessles injury * known coagulopathies * sensitivity to tranexamic acid * medical need in tranexamic acid administration during operation due to bleeding
Where it's running
-
Meir medical center
Kfar Saba, Israel Recruiting -
Meir Medical Center
Kfar Saba, Israel, Israel Not yet recruiting
Study contacts
- Study coordinator: Yair Daykan, M.D
- Email: yair.dykan@gmail.com
- Phone: 0542198231
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.