Using tranexamic acid to reduce blood loss during vaginal hysterectomy
Local Tranexamic Acid During Vaginal Hysterectomy to Reduce Blood Loss
This study is testing if a local injection of tranexamic acid can help reduce blood loss during vaginal hysterectomy surgeries.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 20 Years to 90 Years |
| Sex | Female |
| Sponsor | Meir Medical Center Academic / other |
| Locations | 2 sites (Kfar Saba, Israel and 1 other locations) |
| Trial ID | NCT04760301 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of local tranexamic acid in minimizing blood loss during vaginal hysterectomy procedures. Participants will be randomly assigned to receive either a local injection of tranexamic acid or a placebo (saline) at the start of the surgery. The study will measure the amount of blood loss during the operation to determine if tranexamic acid can significantly reduce bleeding. This approach could provide a simple and effective method to enhance surgical outcomes for patients undergoing this procedure.
Who should consider this trial
Good fit: Ideal candidates are female patients aged 20-90 who are scheduled for a vaginal hysterectomy.
Not a fit: Patients experiencing massive bleeding due to major vessel injury or those with known coagulopathies or sensitivity to tranexamic acid may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could lead to reduced blood loss during vaginal hysterectomies, improving patient safety and recovery.
How similar studies have performed: Other studies have shown promising results with the use of tranexamic acid in surgical settings, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 20-90 years old female patients going through vaginal hysterctomy Exclusion Criteria: * massive bleeding during operation due to major vessles injury * known coagulopathies * sensitivity to tranexamic acid * medical need in tranexamic acid administration during operation due to bleeding
Where this trial is running
Kfar Saba, Israel and 1 other locations
- Meir Medical Center — Kfar Saba, Israel, Israel (Not_yet_recruiting)
- Meir medical center — Kfar Saba, Israel (Recruiting)
Study contacts
- Study coordinator: Yair Daykan, M.D
- Email: yair.dykan@gmail.com
- Phone: 0542198231
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.