Using tranexamic acid to reduce blood loss during cesarean delivery
Prophylactic Role Of Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery : A Prospective Study.
This study tests if giving tranexamic acid before a cesarean delivery can help reduce blood loss for women during the surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Aligarh Muslim University Academic / other |
| Locations | 1 site (Fatehpur, Uttar Pradesh) |
| Trial ID | NCT06604325 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of tranexamic acid, an antifibrinolytic agent, to minimize blood loss during cesarean deliveries. It aims to determine the effectiveness of tranexamic acid when administered alongside other uterotonics before the procedure. Given that postpartum hemorrhage is a leading cause of maternal morbidity and mortality, this approach could provide a significant improvement in patient outcomes. The study will compare the effects of tranexamic acid against a placebo in women undergoing cesarean sections.
Who should consider this trial
Good fit: Ideal candidates are women undergoing elective or emergency cesarean deliveries who are willing to participate.
Not a fit: Patients who are critically ill or have a ruptured uterus or are undergoing cesarean hysterectomy will not benefit from this study.
Why it matters
Potential benefit: If successful, this could significantly reduce the incidence of postpartum hemorrhage and improve maternal health outcomes.
How similar studies have performed: Other studies have shown promising results with tranexamic acid in reducing blood loss in various surgical settings, suggesting potential success in this application.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. The women undergoing cesarean delivery (both elective and emergency) during the study period. 2. Willing to participate in the study after understanding the concept. Exclusion Criteria: 1. Critically ill patient. 2. Not willing to give consent to participate in the study 3. Cases diagnosed with a ruptured uterus or undergoing caesarian hysterectomy during operation.
Where this trial is running
Fatehpur, Uttar Pradesh
- ASJSATDS Medical College — Fatehpur, Uttar Pradesh, India (Recruiting)
Study contacts
- Principal investigator: Muazzam Hasan, Md — Amu
- Study coordinator: Muazzam Hasan, Md
- Email: MUAZZAMSH@GMAIL.COM
- Phone: 9808447427
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.