Using topical lidocaine/prilocaine cream for pain relief during pleurocentesis
Efficacy of Topical Lidocaine/Prilocaine in Pain Management in Pleurocentesis
This study tests whether a cream for numbing pain can work better than a regular injection during a procedure called pleurocentesis for patients who need it.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 118 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Assiut) |
| Trial ID | NCT05984264 on ClinicalTrials.gov |
What this trial studies
This research compares the effectiveness of a topical anesthetic cream containing lidocaine and prilocaine against the standard local anesthetic injection for pain management during pleurocentesis. The study aims to address the common issue of pain associated with the injection process, which can be particularly distressing for patients. By utilizing a topical cream, the goal is to provide a less painful alternative that is easier to administer, especially in settings with limited medical expertise. The trial will involve patients who are scheduled for pleurocentesis and will assess pain levels during the procedure.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who are scheduled to undergo pleurocentesis.
Not a fit: Patients with a known sensitivity to local anesthetics or those on specific anti-arrhythmic medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce procedural pain for patients undergoing pleurocentesis.
How similar studies have performed: Previous studies have shown success with similar topical anesthetic approaches in various medical procedures, suggesting potential efficacy in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All Patients will be prepared for pleurocentesis. Exclusion Criteria: 1. Patients with a known history of sensitivity to local anesthetics of the amide type or to any other component of the product. 2. Patients treated with class III anti-arrhythmic drugs (e.g., amiodarone, bretylium, sotalol, dofetilide).
Where this trial is running
Assiut
- Assuit University Hospital — Assiut, Egypt (Recruiting)
Study contacts
- Principal investigator: Safaa A Eid, MD — Assiut University
- Study coordinator: Safaa A Eid, MD
- Email: safaa_gayed@aun.edu.eg
- Phone: 01002569966
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.