Using tissue grafts to treat wrist osteoarthritis
Official title: Proximal Row Carpectomy With Meniscal Allograft Arthroplasty for Wrist Osteoarthritis
Run by University of Colorado, Denver · NCT05412615 · Data updated 2026-11-12
This study is testing a new surgery using tissue grafts to see if it can help people with wrist osteoarthritis feel better and recover more effectively than using synthetic materials.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 80 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | University of Colorado, Denver Academic / other |
| Locations | 1 site (Englewood, Colorado) |
| Status | Recruiting |
| Started | September 1, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | February 10, 2025 |
| Trial ID | NCT05412615 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 30 to 80 with symptomatic wrist arthritis related to SLAC or SNAC pathology.
✕Probably not a fit
Patients younger than 29 or older than 80, or those with a history of previous wrist osteoarthritis surgery, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of meniscal allograft transplantation in conjunction with proximal row carpectomy for patients suffering from wrist osteoarthritis. The approach focuses on improving allograft stability and minimizing foreign body reactions compared to traditional synthetic materials. Participants will undergo surgical procedures to assess the outcomes of this innovative treatment method.
Why it matters
Potential benefit: If successful, this treatment could provide improved stability and pain relief for patients with wrist osteoarthritis.
How similar studies have gone: Previous studies have indicated better outcomes with allograft use compared to synthetic materials, suggesting a promising avenue for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * symptomatic wrist arthritis associated with SLAC or SNAC pathology * Patients 30 years or older or 80 years or younger Exclusion Criteria: * Patients younger than 29 years or older than 80 years * History of previous surgery related to wrist osteoarthritis
Where it's running
-
UCHealth Steadman Hawkins Clinic Inverness
Englewood, Colorado, United States Recruiting
Study contacts
- Study coordinator: Fraser J Leversedge, MD
- Email: fraser.leversedge@cuanschutz.edu
- Phone: 919-316-0616
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Evaluating wrist and carpal fusion surgeries for pain relief and stability
This study is testing different wrist surgeries to see if they can help people with chronic pain and instability feel better and regain function after other treatments haven't worked.
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Web-based rehab after wrist salvage surgery
A web-based rehabilitation program is tested to see if it works as well as standard in-person rehab after wrist salvage surgery for osteoarthritis.
-
Comparing two surgical options for wrist osteoarthritis
This study is testing which surgery, either proximal row carpectomy or four-corner fusion, works better for people with certain types of wrist osteoarthritis.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.