Using tissue grafts to treat wrist osteoarthritis

Proximal Row Carpectomy With Meniscal Allograft Arthroplasty for Wrist Osteoarthritis

Not applicable Interventional University of Colorado, Denver · NCT05412615

This study is testing a new surgery using tissue grafts to see if it can help people with wrist osteoarthritis feel better and recover more effectively than using synthetic materials.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages30 Years to 80 Years
SexAll
SponsorUniversity of Colorado, Denver Academic / other
Locations1 site (Englewood, Colorado)
Trial IDNCT05412615 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of meniscal allograft transplantation in conjunction with proximal row carpectomy for patients suffering from wrist osteoarthritis. The approach focuses on improving allograft stability and minimizing foreign body reactions compared to traditional synthetic materials. Participants will undergo surgical procedures to assess the outcomes of this innovative treatment method.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 30 to 80 with symptomatic wrist arthritis related to SLAC or SNAC pathology.

Not a fit: Patients younger than 29 or older than 80, or those with a history of previous wrist osteoarthritis surgery, may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide improved stability and pain relief for patients with wrist osteoarthritis.

How similar studies have performed: Previous studies have indicated better outcomes with allograft use compared to synthetic materials, suggesting a promising avenue for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* symptomatic wrist arthritis associated with SLAC or SNAC pathology
* Patients 30 years or older or 80 years or younger

Exclusion Criteria:

* Patients younger than 29 years or older than 80 years
* History of previous surgery related to wrist osteoarthritis

Where this trial is running

Englewood, Colorado

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Wrist Osteoarthritis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.