Using the Current Together After Cancer (CTAC) website to improve follow-up care for colorectal cancer survivors
Official title: A Pragmatic Randomized Controlled Trial to Evaluate the Effectiveness of an Intervention Called Current Together After Cancer (CTAC) to Promote Guideline-Concordant Colorectal Cancer Surveillance
Run by SWOG Cancer Research Network · NCT07018869 · Data updated 2026-11-12
This trial tests whether the CTAC website helps people with resected stage II or III colorectal cancer and a chosen adult supporter get recommended follow-up care that follows guidelines.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1057 (estimated) |
| Sponsor | SWOG Cancer Research Network Research network |
| Locations | 384 sites (Anchorage, Alaska and 383 other locations) |
| Status | Recruiting |
| Started | October 15, 2025 |
| Main results expected | October 28, 2031 |
| Study ends | April 28, 2032 |
| Registry record updated | November 6, 2026 |
| Trial ID | NCT07018869 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with newly diagnosed, surgically resected stage II or III colorectal cancer who have an adult supporter willing to view the website with them and can access web-based content are ideal candidates.
✕Probably not a fit
Patients without an available adult supporter, those unable or unwilling to use online resources, or people with other cancer stages are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This phase III randomized trial compares access to an interactive CTAC intervention website versus a control website for patients with surgically resected stage II or III colorectal cancer. The primary outcome is receipt of guideline-concordant colorectal cancer surveillance at 12 months after registration, with patient-reported knowledge, self-efficacy, and satisfaction with supporter engagement measured at 3 and 16 months. The intervention actively involves an adult supporter chosen by the patient and includes online educational content aimed at improving surveillance management and communication. The study also includes mixed-methods process evaluation to identify implementation barriers and to explore how supporter participation relates to outcomes.
Why it matters
Potential benefit: If successful, CTAC could increase the number of colorectal cancer survivors receiving guideline-based surveillance and help detect recurrences earlier.
How similar studies have gone: Previous web-based and caregiver-supported educational interventions have shown mixed but promising results for improving follow-up care adherence and patient self-efficacy.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * PATIENTS: * Patient participants must have newly diagnosed surgically resected, stage II or stage III colorectal cancer per the timing described below * Patient participants must have an adult in their life who supports them in their colorectal cancer journey who they might be willing to invite to join them in viewing an educational website. This is determined via the question: "Do you have an adult in your life, such as a spouse/partner, family member or friend, who supports you with your colorectal cancer journey and may be willing to view a website with you? When we say, "supports you in your colorectal cancer journey", we mean things like, helping you keep and get to medical appointments, talking with you and/or your doctors about your cancer, or helping you make decisions about your cancer." * Those who respond "no" to the question above will be told that "Because this study is for patients and a supporter to view the website together, you are not eligible for this study, but there may be other studies you are eligible for in the future". * NOTE: The above question will be used to define "supporter" for purposes of this study. Examples of supporters include a spouse, partner, sibling, adult child, another family member, or friend. * NOTE: The supporter does not have to agree to participate in the study in order for the patient to be eligible for this study. Justification for requiring the enrolled patient to have a supporter (whether the supporter is invited or participates) is based on the study's underlying conceptual framework * Patient participants must not have recurrent or metastatic (stage IV) colorectal cancer * Patient participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the efficacy assessment of this intervention * Patient participants must be registered within 90 - 180 days of surgical resection * Patient participants must be ≥ 18 years of age at the time of registration/randomization. The lower cutoff of 18 was determined because the lower age range of patients that may be recruited to Southwest Oncology Group (SWOG) studies is 18 * Patient participants must have Zubrod performance status of 0-2 * Patient participants must be able to read English or Spanish since the website for the intervention and control arm are available in English and Spanish * Patient participants must: 1) be able to complete Patient Reported Outcome (PRO) questionnaires in English or Spanish, and 2) agree to complete PROs at all scheduled timepoints * Patient participants will be encouraged to provide an email address or cell phone number, if possible, for the purpose of being contacted by staff at the University of Michigan who will provide access to the educational website. For those who do not wish to provide or create an email address or a cell phone number, they may still participate with alternate methods * Patient participants must not be enrolled or be planning to enroll in a clinical trial of investigational treatment that includes imaging and/or laboratory monitoring for the duration of this trial * NOTE: Patient participants are allowed to be co-enrolled on other non-treatment clinical trials * SUPPORTER PARTICIPANT: * Supporter participants must be ≥ 18 years of age at the time of registration/randomization * Supporter participants must be able to read English or Spanish since the educational website is available in English and Spanish * Supporter participants must have been identified by the patient as a person who may be willing to join them in reviewing the educational website * PATIENT AND SUPPORTER: * NOTE: As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system * Patient and supporter participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines. This protocol does not permit use of Legally Authorized Representative
Where it's running
-
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, United States Recruiting -
Alaska Breast Care and Surgery LLC
Anchorage, Alaska, United States Recruiting -
Alaska Oncology and Hematology LLC
Anchorage, Alaska, United States Recruiting -
Alaska Women's Cancer Care
Anchorage, Alaska, United States Recruiting -
Katmai Oncology Group
Anchorage, Alaska, United States Recruiting -
Providence Alaska Medical Center
Anchorage, Alaska, United States Recruiting
Show 44 more locations
-
Cancer Center at Saint Joseph's
Phoenix, Arizona, United States Recruiting -
Mercy Hospital Fort Smith
Fort Smith, Arkansas, United States Recruiting -
CARTI Cancer Center
Little Rock, Arkansas, United States Recruiting -
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California, United States Recruiting -
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California, United States Recruiting -
Mercy Cancer Center - Carmichael
Carmichael, California, United States Recruiting -
Mercy San Juan Medical Center
Carmichael, California, United States Recruiting -
Mercy Cancer Center - Elk Grove
Elk Grove, California, United States Recruiting -
Mercy Cancer Center
Merced, California, United States Recruiting -
Providence Queen of The Valley
Napa, California, United States Recruiting -
Mercy Cancer Center - Rocklin
Rocklin, California, United States Recruiting -
Mercy Cancer Center - Sacramento
Sacramento, California, United States Recruiting -
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California, United States Recruiting -
Mission Hope Medical Oncology - Santa Maria
Santa Maria, California, United States Recruiting -
Providence Medical Foundation - Santa Rosa
Santa Rosa, California, United States Recruiting -
Providence Santa Rosa Memorial Hospital
Santa Rosa, California, United States Recruiting -
Saint Joseph's Medical Center
Stockton, California, United States Recruiting -
Woodland Memorial Hospital
Woodland, California, United States Recruiting -
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, United States Recruiting -
Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado, United States Recruiting -
Saint Francis Cancer Center
Colorado Springs, Colorado, United States Recruiting -
CommonSpirit Cancer Center Mercy
Durango, Colorado, United States Recruiting -
Mercy Medical Center
Durango, Colorado, United States Recruiting -
Saint Anthony Hospital
Lakewood, Colorado, United States Recruiting -
Longmont United Hospital
Longmont, Colorado, United States Recruiting -
Saint Mary Corwin Medical Center
Pueblo, Colorado, United States Recruiting -
Saint Anthony North Hospital
Westminster, Colorado, United States Recruiting -
Beebe Medical Center
Lewes, Delaware, United States Recruiting -
Beebe South Coastal Health Campus
Millville, Delaware, United States Recruiting -
Helen F Graham Cancer Center
Newark, Delaware, United States Recruiting -
Medical Oncology Hematology Consultants PA
Newark, Delaware, United States Recruiting -
Christiana Care Health System-Christiana Hospital
Newark, Delaware, United States Recruiting -
Beebe Health Campus
Rehoboth Beach, Delaware, United States Recruiting -
Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware, United States Recruiting -
Schulze Family Foundation Cancer Clinic - Bonita Health Center
Bonita Springs, Florida, United States Recruiting -
Holy Cross Hospital
Fort Lauderdale, Florida, United States Recruiting -
Regional Cancer Center-Lee Memorial Health System
Fort Myers, Florida, United States Recruiting -
Augusta University Medical Center
Augusta, Georgia, United States Recruiting -
Northeast Georgia Medical Center Braselton
Braselton, Georgia, United States Recruiting -
Northeast Georgia Medical Center-Gainesville
Gainesville, Georgia, United States Recruiting -
The Longstreet Clinic - Gainesville
Gainesville, Georgia, United States Recruiting -
Memorial Health University Medical Center
Savannah, Georgia, United States Recruiting -
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii, United States Recruiting -
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii, United States Recruiting
+334 more sites. See ClinicalTrials.gov for the full list.
Study contacts
- Principal investigator: Christine M Veenstra — SWOG Cancer Research Network
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Predicting who will benefit from adjuvant chemotherapy in stage II–III colorectal cancer using tumor splicing patterns
This project tests whether a tumor splicing signature from surgical tissue can help predict which people with stage II–III colorectal cancer will benefit from adjuvant chemotherapy.
-
Understanding locoregional recurrence in advanced colon cancer
This study looks at how and why advanced colon cancer can come back in certain patients to see if new blood tests can help predict their outcomes.
-
Blood test for early detection of colorectal cancer and adenomas
This study is testing a new blood test to see if it can help find early signs of colorectal cancer and adenomas in people who are already scheduled for a colonoscopy.
-
Detecting early onset colorectal cancer using a blood test
This study is testing a new blood test that looks for specific markers to help find early signs of colorectal cancer in young adults.
-
Predicting recurrence in stage II/III colorectal cancer after chemotherapy
This study is trying to create a test that can help predict if people with stage II/III colorectal cancer will have their cancer come back after chemotherapy.
-
Assessing minimal residual disease in colorectal cancer using blood tests
This study is testing if a blood test for cancer DNA can help doctors find out which colorectal cancer patients are at risk of their cancer coming back after surgery and if they need extra treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.