Clinical trial Recruiting at 383 sites Phase 3 Interventional Ages 18 and up

Using the Current Together After Cancer (CTAC) website to improve follow-up care for colorectal cancer survivors

Official title: A Pragmatic Randomized Controlled Trial to Evaluate the Effectiveness of an Intervention Called Current Together After Cancer (CTAC) to Promote Guideline-Concordant Colorectal Cancer Surveillance

Run by SWOG Cancer Research Network · NCT07018869 · Data updated 2026-11-12

This trial tests whether the CTAC website helps people with resected stage II or III colorectal cancer and a chosen adult supporter get recommended follow-up care that follows guidelines.

More Colorectal Cancer Stage III trials

Quick facts

PhasePhase 3
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1057 (estimated)
SponsorSWOG Cancer Research Network
Research network
Locations384 sites (Anchorage, Alaska and 383 other locations)
StatusRecruiting
StartedOctober 15, 2025
Main results expectedOctober 28, 2031
Study endsApril 28, 2032
Registry record updatedNovember 6, 2026
Trial IDNCT07018869 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with newly diagnosed, surgically resected stage II or III colorectal cancer who have an adult supporter willing to view the website with them and can access web-based content are ideal candidates.

Probably not a fit

Patients without an available adult supporter, those unable or unwilling to use online resources, or people with other cancer stages are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This phase III randomized trial compares access to an interactive CTAC intervention website versus a control website for patients with surgically resected stage II or III colorectal cancer. The primary outcome is receipt of guideline-concordant colorectal cancer surveillance at 12 months after registration, with patient-reported knowledge, self-efficacy, and satisfaction with supporter engagement measured at 3 and 16 months. The intervention actively involves an adult supporter chosen by the patient and includes online educational content aimed at improving surveillance management and communication. The study also includes mixed-methods process evaluation to identify implementation barriers and to explore how supporter participation relates to outcomes.

Why it matters

Potential benefit: If successful, CTAC could increase the number of colorectal cancer survivors receiving guideline-based surveillance and help detect recurrences earlier.

How similar studies have gone: Previous web-based and caregiver-supported educational interventions have shown mixed but promising results for improving follow-up care adherence and patient self-efficacy.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* PATIENTS:
* Patient participants must have newly diagnosed surgically resected, stage II or stage III colorectal cancer per the timing described below
* Patient participants must have an adult in their life who supports them in their colorectal cancer journey who they might be willing to invite to join them in viewing an educational website. This is determined via the question: "Do you have an adult in your life, such as a spouse/partner, family member or friend, who supports you with your colorectal cancer journey and may be willing to view a website with you? When we say, "supports you in your colorectal cancer journey", we mean things like, helping you keep and get to medical appointments, talking with you and/or your doctors about your cancer, or helping you make decisions about your cancer."

  * Those who respond "no" to the question above will be told that "Because this study is for patients and a supporter to view the website together, you are not eligible for this study, but there may be other studies you are eligible for in the future".
  * NOTE: The above question will be used to define "supporter" for purposes of this study. Examples of supporters include a spouse, partner, sibling, adult child, another family member, or friend.
  * NOTE: The supporter does not have to agree to participate in the study in order for the patient to be eligible for this study. Justification for requiring the enrolled patient to have a supporter (whether the supporter is invited or participates) is based on the study's underlying conceptual framework
* Patient participants must not have recurrent or metastatic (stage IV) colorectal cancer
* Patient participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the efficacy assessment of this intervention
* Patient participants must be registered within 90 - 180 days of surgical resection
* Patient participants must be ≥ 18 years of age at the time of registration/randomization. The lower cutoff of 18 was determined because the lower age range of patients that may be recruited to Southwest Oncology Group (SWOG) studies is 18
* Patient participants must have Zubrod performance status of 0-2
* Patient participants must be able to read English or Spanish since the website for the intervention and control arm are available in English and Spanish
* Patient participants must: 1) be able to complete Patient Reported Outcome (PRO) questionnaires in English or Spanish, and 2) agree to complete PROs at all scheduled timepoints
* Patient participants will be encouraged to provide an email address or cell phone number, if possible, for the purpose of being contacted by staff at the University of Michigan who will provide access to the educational website. For those who do not wish to provide or create an email address or a cell phone number, they may still participate with alternate methods
* Patient participants must not be enrolled or be planning to enroll in a clinical trial of investigational treatment that includes imaging and/or laboratory monitoring for the duration of this trial

  * NOTE: Patient participants are allowed to be co-enrolled on other non-treatment clinical trials
* SUPPORTER PARTICIPANT:
* Supporter participants must be ≥ 18 years of age at the time of registration/randomization
* Supporter participants must be able to read English or Spanish since the educational website is available in English and Spanish
* Supporter participants must have been identified by the patient as a person who may be willing to join them in reviewing the educational website
* PATIENT AND SUPPORTER:
* NOTE: As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system

  * Patient and supporter participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines. This protocol does not permit use of Legally Authorized Representative

Where it's running

  • Anchorage Associates in Radiation Medicine
    Anchorage, Alaska, United States
    Recruiting
  • Alaska Breast Care and Surgery LLC
    Anchorage, Alaska, United States
    Recruiting
  • Alaska Oncology and Hematology LLC
    Anchorage, Alaska, United States
    Recruiting
  • Alaska Women's Cancer Care
    Anchorage, Alaska, United States
    Recruiting
  • Katmai Oncology Group
    Anchorage, Alaska, United States
    Recruiting
  • Providence Alaska Medical Center
    Anchorage, Alaska, United States
    Recruiting
Show 44 more locations
  • Cancer Center at Saint Joseph's
    Phoenix, Arizona, United States
    Recruiting
  • Mercy Hospital Fort Smith
    Fort Smith, Arkansas, United States
    Recruiting
  • CARTI Cancer Center
    Little Rock, Arkansas, United States
    Recruiting
  • Mission Hope Medical Oncology - Arroyo Grande
    Arroyo Grande, California, United States
    Recruiting
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center
    Burbank, California, United States
    Recruiting
  • Mercy Cancer Center - Carmichael
    Carmichael, California, United States
    Recruiting
  • Mercy San Juan Medical Center
    Carmichael, California, United States
    Recruiting
  • Mercy Cancer Center - Elk Grove
    Elk Grove, California, United States
    Recruiting
  • Mercy Cancer Center
    Merced, California, United States
    Recruiting
  • Providence Queen of The Valley
    Napa, California, United States
    Recruiting
  • Mercy Cancer Center - Rocklin
    Rocklin, California, United States
    Recruiting
  • Mercy Cancer Center - Sacramento
    Sacramento, California, United States
    Recruiting
  • Pacific Central Coast Health Center-San Luis Obispo
    San Luis Obispo, California, United States
    Recruiting
  • Mission Hope Medical Oncology - Santa Maria
    Santa Maria, California, United States
    Recruiting
  • Providence Medical Foundation - Santa Rosa
    Santa Rosa, California, United States
    Recruiting
  • Providence Santa Rosa Memorial Hospital
    Santa Rosa, California, United States
    Recruiting
  • Saint Joseph's Medical Center
    Stockton, California, United States
    Recruiting
  • Woodland Memorial Hospital
    Woodland, California, United States
    Recruiting
  • Penrose-Saint Francis Healthcare
    Colorado Springs, Colorado, United States
    Recruiting
  • Rocky Mountain Cancer Centers-Penrose
    Colorado Springs, Colorado, United States
    Recruiting
  • Saint Francis Cancer Center
    Colorado Springs, Colorado, United States
    Recruiting
  • CommonSpirit Cancer Center Mercy
    Durango, Colorado, United States
    Recruiting
  • Mercy Medical Center
    Durango, Colorado, United States
    Recruiting
  • Saint Anthony Hospital
    Lakewood, Colorado, United States
    Recruiting
  • Longmont United Hospital
    Longmont, Colorado, United States
    Recruiting
  • Saint Mary Corwin Medical Center
    Pueblo, Colorado, United States
    Recruiting
  • Saint Anthony North Hospital
    Westminster, Colorado, United States
    Recruiting
  • Beebe Medical Center
    Lewes, Delaware, United States
    Recruiting
  • Beebe South Coastal Health Campus
    Millville, Delaware, United States
    Recruiting
  • Helen F Graham Cancer Center
    Newark, Delaware, United States
    Recruiting
  • Medical Oncology Hematology Consultants PA
    Newark, Delaware, United States
    Recruiting
  • Christiana Care Health System-Christiana Hospital
    Newark, Delaware, United States
    Recruiting
  • Beebe Health Campus
    Rehoboth Beach, Delaware, United States
    Recruiting
  • Christiana Care Health System-Wilmington Hospital
    Wilmington, Delaware, United States
    Recruiting
  • Schulze Family Foundation Cancer Clinic - Bonita Health Center
    Bonita Springs, Florida, United States
    Recruiting
  • Holy Cross Hospital
    Fort Lauderdale, Florida, United States
    Recruiting
  • Regional Cancer Center-Lee Memorial Health System
    Fort Myers, Florida, United States
    Recruiting
  • Augusta University Medical Center
    Augusta, Georgia, United States
    Recruiting
  • Northeast Georgia Medical Center Braselton
    Braselton, Georgia, United States
    Recruiting
  • Northeast Georgia Medical Center-Gainesville
    Gainesville, Georgia, United States
    Recruiting
  • The Longstreet Clinic - Gainesville
    Gainesville, Georgia, United States
    Recruiting
  • Memorial Health University Medical Center
    Savannah, Georgia, United States
    Recruiting
  • Hawaii Cancer Care Inc - Waterfront Plaza
    Honolulu, Hawaii, United States
    Recruiting
  • Queen's Cancer Cenrer - POB I
    Honolulu, Hawaii, United States
    Recruiting

+334 more sites. See ClinicalTrials.gov for the full list.

Study contacts

  • Principal investigator: Christine M Veenstra — SWOG Cancer Research Network

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.