Using targeted brain stimulation to improve upper limb movement after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of targeted high-definition transcranial direct current stimulation (tDCS) on reducing motor impairments in the upper limb following a stroke. Participants will undergo a series of interventions involving different stimulation techniques, including anodal and cathodal stimulation, in a randomized and double-blinded manner. The study aims to assess the impact of these interventions on motor function by utilizing a subject-specific head model to optimize stimulation parameters. The total duration of participation is approximately 10 weeks, including four intervention visits and assessments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Paresis confined to one side, with substantial motor impairment of the paretic upper limb
* Capacity to provide informed consent

Exclusion Criteria:

* Muscle tone abnormalities and motor or sensory impairment in the non-paretic limb
* Severe wasting or contracture or significant sensory deficits in the paretic upper limb
* Severe cognitive or affective dysfunction that prevents normal communication and understanding of consent or instruction
* Severe concurrent medical problems (e.g. cardiorespiratory impairment)
* Using a pacemaker
* Metal implants in the head
* Known adverse reactions to TMS and tDCS
* Pregnant

Where it's running

• Carle Foundation Hospital
  Urbana, Illinois, United States Recruiting

Study contacts

• Study coordinator: Yuan Yang, PhD
• Email: yuan.yang@carle.com
• Phone: 217-244-5870

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

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• Dual-task balance training plus computer-based cognitive training after stroke

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  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.