Using Tamsulosin to Reduce Urinary Retention After Thoracic Surgery
Official title: Post Operative Urinary Retention (POUR) Following Thoracic Oncological Surgery
Run by Hackensack Meridian Health · NCT05657990 · Data updated 2026-11-12
This study is testing if taking Tamsulosin for a week before thoracic surgery can help older men avoid problems with urination afterwards.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 55 Years and up |
| Sex | Men only |
| Enrollment | 46 (estimated) |
| Sponsor | Hackensack Meridian Health Academic / other |
| Locations | 4 sites (Brick, New Jersey and 3 other locations) |
| Status | Recruiting |
| Started | April 3, 2023 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | September 9, 2026 |
| Trial ID | NCT05657990 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are males aged 55 and older scheduled for thoracic oncological surgery.
✕Probably not a fit
Patients currently using Tamsulosin or those with certain medical conditions such as hypotension or heart failure may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This feasibility study investigates whether Tamsulosin can reduce the incidence of postoperative urinary retention (POUR) in older men undergoing thoracic oncological surgery. The study focuses on men aged 55 and older who are scheduled for surgery and will take Tamsulosin for seven days prior to the procedure. Researchers will measure spontaneous voids and assess residual urine post-surgery to evaluate the effectiveness of the treatment. The goal is to determine if Tamsulosin can improve urinary function and reduce complications associated with POUR.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of urinary retention and related complications in older men after thoracic surgery.
How similar studies have gone: Previous studies have indicated that Tamsulosin may effectively reduce urinary retention, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Males * ≥55 years old * Planned thoracic oncological surgical procedure of a video assisted oncological surgical procedure for suspected or confirmed cancer. * Surgery scheduled more than 7 days from the time of consent Exclusion Criteria: * Using Tamsulosin already * Known allergy to Tamsulosin or sulfa drugs * Current use of Boceprevir * Resting systolic blood pressure \<100 * Orthostatic hypotension of \>20mm Hg systolic and/or 10mm Hg diastolic pressure from sitting to standing (after 2 minutes of standing) as measured at the time of consent * Known history of hypotension * Known diagnosis of congestive heart failure (CHF) and valvular heart disease * History of prior prostate surgery (prostatectomy, trans-urethral resection)
Where it's running
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Ocean University Medical Center
Brick, New Jersey, United States Recruiting -
South Ocean University Medical Center
Manahawkin, New Jersey, United States Recruiting -
Jersey Shore University Medical Center
Neptune City, New Jersey, United States Recruiting -
Riverview Medical Center
Red Bank, New Jersey, United States Recruiting
Study contacts
- Principal investigator: Thomas Bauer, MD — Hackensack Meridian Health
- Study coordinator: Denise Theiler, RN
- Email: Denise.Theiler@hmhn.org
- Phone: 7327763301
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.