Using sticky bone with or without EDTA to treat gum recession
Evaluation of Sticky Bone With or Without EDTA Root Surface Biomodification for Treatment of Gingival Recession: Randomized Controlled Clinical Study
NA · Kafrelsheikh University · NCT04980066
This study is testing if using sticky bone with or without a special solution can help people with gum recession feel better and improve their smiles.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Kafrelsheikh University (other) |
| Locations | 1 site (Kafr El-sheikh) |
| Trial ID | NCT04980066 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of sticky bone, with or without the addition of EDTA, in treating gingival recession, a common issue in periodontal disease that can lead to aesthetic concerns and sensitivity. The approach utilizes injectable platelet-rich fibrin (i-PRF), a bioactive agent that promotes tissue regeneration, and examines how EDTA may enhance connective tissue attachment to the root surface. Participants will be selected based on specific criteria related to their gum health and overall dental condition, ensuring a focused assessment of treatment outcomes.
Who should consider this trial
Good fit: Ideal candidates are non-smoking individuals with isolated maxillary Miller I/II recession defects and no significant dental issues.
Not a fit: Patients who are pregnant or have systemic diseases that affect periodontal health may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve gum health and aesthetics for patients suffering from gingival recession.
How similar studies have performed: While the use of i-PRF in regenerative treatments has shown good outcomes, the specific combination of sticky bone and EDTA for this purpose is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Miller I/II isolated maxillary recession defects. * No abrasion, caries, or cervical restorations and presence of identifiable cementoenamel junction (CEJ). * No occlusal interferences. * Full-mouth plaque index (PI) and gingival index (GI) scores of \< 1. * Non-smokers. Exclusion Criteria: * Pregnant patients * Presence of systemic disease or taking medication that interfere with periodontium
Where this trial is running
Kafr El-sheikh
- Faculty of Dentistry, Kafrelsheikh University — Kafr El-sheikh, Egypt (RECRUITING)
Study contacts
- Principal investigator: Dalia R Issa, PhD — Kafrelsheikh University
- Study coordinator: Dalia R Issa, PhD
- Email: dalia_rasheed@hotmail.com
- Phone: 01007753636
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gingival Recession, i-PRF, EDTA