Clinical trial Recruiting at 1 site Interventional Ages 50 to 80

Using spinal cord stimulation to treat symptoms of Parkinsonism

Official title: Spinal Cord Stimulation for Parkinsonism: a Single-center, Single-arm Open Trial

Run by Ruijin Hospital · NCT05171205 · Data updated 2026-11-12

This study is testing if spinal cord stimulation can help improve symptoms like low blood pressure, urinary issues, sleep problems, and speech difficulties in people with Parkinsonism.

More Parkinson's Disease and Parkinsonism trials

Quick facts

Study typeInterventional
Ages50 Years to 80 Years
SexAll
Enrollment50 (estimated)
SponsorRuijin Hospital
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedMay 1, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedMay 9, 2025
Trial IDNCT05171205 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 50 to 80 who have been diagnosed with Parkinsonism and can comply with study instructions.

Probably not a fit

Patients with severe depression, anxiety, or other non-neurological conditions that hinder participation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of spinal cord stimulation (SCS) as a treatment for various symptoms associated with Parkinsonism, including orthostatic hypotension, urinary retention, sleep disturbances, dysarthria, and dysphagia. The study will be conducted at a single center and aims to assess patient improvements before and after SCS treatment. By leveraging the established safety and reversibility of SCS, this innovative approach seeks to provide new therapeutic options for patients suffering from Parkinsonism.

Why it matters

Potential benefit: If successful, this treatment could significantly improve the quality of life for patients with Parkinsonism by alleviating debilitating symptoms.

How similar studies have gone: While spinal cord stimulation has been successfully used for chronic pain management, this specific application for Parkinsonism is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

1. Diagnosed with parkinsonism according to MDS clinical diagnostic criteria for Parkinson's disease
2. Aged between 50 and 80 years
3. Able and willing to follow instruction of the researcher
4. No other conditions that the researchers consider inappropriate for inclusion

Exclusion criteria:

1. Severe depression (HAMD-17 above 17 as moderate to severe) or anxiety
2. Pregnancy
3. History of alcoholism
4. Non-neurological disease-related symptoms that prevent patients from participation in the study

Where it's running

  • Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.