Using Spectral CT to Diagnose Myocarditis in Patients with Chest Pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of Spectral CT technology in diagnosing myocarditis and other non-myocarditis causes of acute chest pain in patients with low to intermediate probability of coronary artery disease. Participants will undergo CT examinations that utilize advanced imaging techniques to analyze myocardial tissue characteristics, such as edema and fibrosis. The study will collect clinical and laboratory data alongside imaging results to enhance diagnostic accuracy. By leveraging innovative imaging technology, the study seeks to improve the identification of cardiac conditions in emergency settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age greater than or equal to 18 years;
* patients with acute chest pain and indication for triple-rule-out CT or coronary CT examination, i.e. low/intermediate probability of acute coronary artery disease, ECG and/or troponin not diagnostic or altered;
* Obtaining informed consent

Exclusion Criteria:

* Absolute contraindications to CT examination and/or iodinated mdc administration (i.e. pregnancy, severe renal impairment in non-dialysis patients with GFR \< 15-30 ml/min/1.73m2 );
* CT examinations that do not allow diagnostic information to be provided because they are assessed as quality too scarce and not interpretable (affected by artifacts such as motion artifacts)

Where it's running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna
  Bologna, Italy Recruiting

Study contacts

• Principal investigator: Vincenzo Russo, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
• Study coordinator: Vincenzo Russo, MD
• Email: vincenzo.russo@aosp.bo.it
• Phone: +390512144747

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.