Using social networks to improve HIV care for young Black men and women

Harnessing Social Network Support to Improve Retention in Care and Viral Suppression Among People Living With HIV in Chicago and Alabama: A Hybrid Type I Effectiveness-implementation Trial

NA · University of Chicago · NCT05723653

This study is testing a new program that uses support from friends and family to help young Black men and women with HIV stay in care and manage their health better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment900 (estimated)
Ages18 Years to 49 Years
SexAll
SponsorUniversity of Chicago (other)
Locations7 sites (Birmingham, Alabama and 6 other locations)
Trial IDNCT05723653 on ClinicalTrials.gov

What this trial studies

This trial tests Project nGage, an intervention designed to enhance retention in HIV care and promote viral suppression among young Black men and women aged 18-49. It leverages existing social networks by identifying Support Confidants who can provide essential social support. The study will take place in high-burden areas in Chicago, Illinois, and Alabama, focusing on individuals who have missed HIV care visits or are not virally suppressed. The intervention includes a single in-person session with trained facilitators to engage both the Index participant and their Support Confidant.

Who should consider this trial

Good fit: Ideal candidates are Black/African American individuals aged 18-49 who have missed HIV care visits or are not virally suppressed.

Not a fit: Patients who are not Black/African American or do not meet the age and HIV care criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve HIV care engagement and health outcomes for young Black men and women.

How similar studies have performed: Other studies have shown promise in using social networks for health interventions, but this specific approach is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria for Index Participants:

* Aged 18-49 years old, inclusive
* Speak English
* Own a cell phone not shared with anyone else
* Have missed at least one HIV care scheduled visit or have not been virally suppressed in the past 24 months.
* Resides in Chicagoland, Illinois or Alabama

Exclusion Criteria for Index Men:

* If a participant fails to meet all inclusion criteria

Inclusion Criteria for Support Confidants:

* Index agrees to engage the Support Confidant
* Age 18 years or older
* Speaks English
* Owns a cell phone not shared with others
* Is not a romantic/sexual partner of the Index participant

Exclusion Criteria:

* Romantic/Sexual partners of Index participant
* Relationship strain or abuse present in Index-Support Confidant relationship

Where this trial is running

Birmingham, Alabama and 6 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: HIV Seropositivity, HIV care engagement, HIV viral suppression, Social support, Social networks

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.