Using simple vital-sign scores to guide care for COVID-19 patients
The Combined Usage of Clinical Physiological Finding in Management of COVID 19 Patients
St. Martin De Porress Hospital · NCT07504341
This project tests whether simple vital-sign scores (like shock index, modified and respiratory-adjusted shock indices) can help track and predict worsening or improvement in people hospitalized with COVID-19.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 15000 (estimated) |
| Sex | All |
| Sponsor | St. Martin De Porress Hospital (other) |
| Locations | 2 sites (Chiayi City and 1 other locations) |
| Trial ID | NCT07504341 on ClinicalTrials.gov |
What this trial studies
This observational study uses routinely recorded physiological data—blood pressure, heart rate, respiratory rate, and level of consciousness—from patients treated at the participating hospitals between May 2022 and March 2027. Investigators will calculate indices such as Shock Index, Modified Shock Index, Age Shock Index, Age Modified Shock Index, and Respiratory Adjusted Shock Index and compare them to clinical courses. The work aims to develop easy-to-use bedside or electronic tools, potentially aided by artificial intelligence, to flag early deterioration and guide timely treatment. The approach is intended for settings with varied illness severity and limited manpower to support rapid triage and monitoring.
Who should consider this trial
Good fit: People hospitalized with COVID-19 at the participating St. Martin De Porres Hospital sites between May 2022 and March 2027 who have complete vital-sign records (blood pressure, heart rate, respiratory rate, and level of consciousness) are the intended candidates.
Not a fit: Patients with incomplete or missing clinical records, those treated entirely outside the May 2022–March 2027 window, or cases lacking the required vital-sign data would not be included and are unlikely to benefit.
Why it matters
Potential benefit: If successful, these simple, bedside or electronic scores could give earlier warning of clinical deterioration and help guide timely treatment and resource allocation.
How similar studies have performed: Shock-index approaches have shown usefulness in sepsis, trauma, and some COVID-19 cohorts, but respiratory-adjusted and certain age-modified indices are less widely validated and remain relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Reviewing the patient's medical history, the primary focus was on hospital records and existing physiological parameters such as blood pressure, heart rate, respiratory rate, and level of consciousness. The patient received treatment at the hospital between May 2022 and March 2027 Exclusion Criteria: * Excluding patients with incomplete clinical data or missing information in their medical records.
Where this trial is running
Chiayi City and 1 other locations
- St. Martin De Porres Hospital — Chiayi City, Taiwan (RECRUITING)
- St. Martin De Porres Hospital — Tainan, Taiwan (RECRUITING)
Study contacts
- Principal investigator: Chia-Hsi Chen, Physician — St. Martin De Porress Hospital
- Study coordinator: Chia-Hsi Chen, Physician
- Email: urologist3509@gmail.com
- Phone: 886-5-2756000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: COVID-19, shock index, mordified shock index, Age shock index, respiratory adjusted shock index