Using silver diamine fluoride to treat tooth sensitivity in older adults
A Clinical Protocol on the Effectiveness of 38% Silver Diamine Fluoride in Reducing Dentine Hypersensitivity on Exposed Root Surface in Older Chinese Adults
This study is testing if silver diamine fluoride can help reduce tooth sensitivity in older adults aged 65 and over.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 166 (estimated) |
| Ages | 65 Years to 100 Years |
| Sex | All |
| Sponsor | The University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT05392868 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of silver diamine fluoride (SDF) in reducing dentine hypersensitivity among older adults aged 65 and over. The study involves a double-blinded, randomized design with 166 participants who will receive either SDF or potassium nitrate treatment every four weeks. Participants will be assessed for sensitivity using a calibrated clinical examination method. The goal is to determine if SDF can significantly alleviate pain associated with dentine hypersensitivity in this population.
Who should consider this trial
Good fit: Ideal candidates are generally healthy older adults aged 65 or over with self-perceived tooth sensitivity scores of 8 or above.
Not a fit: Patients with major systemic diseases, those using desensitizing agents recently, or those with hypersensitivity due to other dental conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the quality of life for older adults suffering from dentine hypersensitivity.
How similar studies have performed: While there is limited data on the effectiveness of SDF specifically for older adults, similar studies have shown promise in using SDF for dentine hypersensitivity in various populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * generally healthy; * no known or suspected allergy to the study ingredients or materials * have all active dental diseases under control but reported hypersensitivity Exclusion Criteria: * using any desensitizing agent within one month * have major systemic diseases such as cancer * receive medications that may affect pain perception within one month * have dentine hypersensitivity due to other dental conditions such as caries * are not able to give written consent
Where this trial is running
Hong Kong
- The University of Hong Kong — Hong Kong, China (Recruiting)
Study contacts
- Study coordinator: Chun Hung Chu, PhD
- Email: chchu@hku.hk
- Phone: (+852)28590287
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.