Using Sensorimotor Reorganization After Upper Limb Amputation to Help Protheses
Official title: Using Sensorimotor Reorganization Following Upper Limb Amputation to Improve Prosthetic Control
Run by Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est · NCT07666204 · Data updated 2026-11-12
This study tests whether tapping into induced sensations and phantom movements can improve how people control and feel their prosthetic arm.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est Academic / other |
| Locations | 2 sites (Nancy and 1 other locations) |
| Status | Recruiting |
| Started | April 15, 2026 |
| Main results expected | April 30, 2030 |
| Study ends | April 30, 2030 |
| Registry record updated | June 24, 2026 |
| Trial ID | NCT07666204 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older with an upper-limb amputation or agenesis above the wrist who can communicate in French and have social security affiliation.
✕Probably not a fit
Individuals whose condition or neural reorganization does not respond to the sensorimotor approach may not experience improved prosthetic control.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial explores how changes in the brain after upper limb loss can be leveraged to improve prosthetic control and sensory feedback. Participants will undergo characterization, mapping, and classification of phantom sensations and motor patterns, with interventions aimed at enhancing prosthetic use while reducing cognitive load. The approach combines sensorimotor mapping with phantom mobility concepts to support more natural and intuitive prosthesis control. The study emphasizes safety and relies on structured interviews conducted in French to capture subjective experiences. The locations include neurorehabilitation and robotics research centers in Nancy and Rennes, with collaboration from movement science and computer science institutes.
Why it matters
Potential benefit: If successful, participants could experience easier, more intuitive prosthetic control and better sensory feedback.
How similar studies have gone: Prior work in sensorimotor reorganization and phantom sensations has shown potential gains in prosthetic control, though this exact approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * people aged 18 or more * amputation or agenesis of one uper limb, above the wrist or higher * understanding of the French language and the ability to express onself in that language (for semi-structured interviews) * affiliation to a social security programm Exclusion Criteria: * history of progressive psychiatric or neurological disorders or disorders with residual effects * pregnant or breastfeeding woman * minor * an adult under legal guardianship * pain influencing movement (trunk, residual limb, phantom limb, contralateral limb)
Where it's running
-
Institut Régional de Médecine Physique et de Réadaptation, Filière Locomoteur
Nancy, France Recruiting -
Fondation Saint-Hélier
Rennes, France Recruiting
Study contacts
- Study coordinator: Amélie Touillet
- Email: amelie.touillet@ugecam.assurance-maladie.fr
- Phone: +333 83 52 97 00
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.