Using rTMS with AI to help children with dyslexia improve reading skills
Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) as an Adjunct to AI Enabled Remedial Intervention in School Going Children (Aged 6-18 Years) Having Specific Learning Disorder With Dyslexia
This study is testing if using a special brain treatment along with an AI program can help children with dyslexia improve their reading skills better than regular methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 6 Years to 18 Years |
| Sex | All |
| Sponsor | All India Institute of Medical Sciences, New Delhi Academic / other |
| Locations | 1 site (Delhi) |
| Trial ID | NCT05923645 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of high-frequency repetitive Transcranial Magnetic Stimulation (Hf rTMS) as an adjunct to an AI-enabled remedial intervention for children diagnosed with dyslexia. The trial will involve screening school-aged children who meet the DSM-5 criteria for specific learning disorder (SLD) with dyslexia, followed by a structured intervention combining AI-based phonological training and rTMS over six weeks. Participants will undergo baseline assessments, including neuroimaging for a subset, to evaluate their reading abilities before and after the intervention. The goal is to determine if this combined approach can enhance reading skills more effectively than traditional methods alone.
Who should consider this trial
Good fit: Ideal candidates are Indian school-aged children between 6-18 years old diagnosed with dyslexia and whose parents are willing to participate.
Not a fit: Patients who have received remedial intervention within the last 12 weeks or have other neurological or psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve reading abilities in children with dyslexia, offering a new avenue for treatment.
How similar studies have performed: Previous studies have shown promising results with neuromodulation techniques like rTMS in treating learning disorders, suggesting potential for success in this novel combination approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Indian school going children aged 6-18 years having specific learning disorder (SLD) with dyslexia diagnosed by DSM-5 criteria * English as one of the languages in school * Parents willing for the study Exclusion Criteria: * Parents not willing to participate or follow up at desired frequency of study * Child who has already received or is on remedial intervention within last 12 weeks provided by Child Psychologist/ Clinician/Psychiatrist * Children who participated in a completed DM dissertation on remedial program in SLD * Child already on any psychotropic medications * Neurological or psychiatric disorder other than comorbid disorders of SLD * Uncontrolled epilepsy as defined by seizure frequency \>1/month for preceding 3 months * Severe concurrent illness or disease or unstable medical conditions * Any contraindications for MRI like presence of pacemaker, metallic implant * Any contraindications for TMS like Implanted electronic device and non-removable metallic objects near coil e.g. pacemaker, cochlear implant; presence of ferromagnetic metal in the head outside the mouth; on medication lowering seizure threshold.
Where this trial is running
Delhi
- All India Institute of Medical Sciences — Delhi, India (Recruiting)
Study contacts
- Principal investigator: Sheffali Gulati — All India Institute of Medical Sciences, New Delh
- Study coordinator: Sheffali Gulati
- Email: sheffaligulati@gmail.com
- Phone: 01126594679
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.