Using rTMS to Improve Balance and Gait in Spinocerebellar Ataxia
Repetitive Transcranial Magnetic Stimulation Improves Functional Performance in Spinocerebellar Ataxia
NA · Changhua Christian Hospital · NCT05973019
This study is testing if a new brain stimulation treatment can help improve balance and walking in people with Spinocerebellar Ataxia type 3 who can walk on their own.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Changhua Christian Hospital (other) |
| Locations | 2 sites (Changhua and 1 other locations) |
| Trial ID | NCT05973019 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of repetitive transcranial magnetic stimulation (rTMS) on balance and gait in patients with Spinocerebellar Ataxia type 3. The research aims to determine if high-frequency rTMS can enhance limb functional performance, as previous studies have shown mixed results with varying frequencies. Participants will undergo rTMS treatment while their walking speed and balance are assessed. The study focuses specifically on individuals who can walk independently, with or without assistive devices.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with Spinocerebellar Ataxia type 3 who can walk independently.
Not a fit: Patients with a history of epilepsy, unstable blood pressure, or other specified exclusions may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve mobility and quality of life for patients with Spinocerebellar Ataxia.
How similar studies have performed: Previous studies have shown varying success with rTMS in improving functional performance, but this specific approach targeting SCA type 3 is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * SCA type 3 * independently walk with/without an assistive device * SARA greater than 3 Exclusion Criteria: * Epilepsy history * Unstable blood pressure * Brain Trauma * Alcoholism, drug abuse, antipsychotics drug use * Metallic hardware (e.g. - cochlear implants, brain stimulators or electrodes, aneurysm clips) anywhere in head. * Dementia, depression
Where this trial is running
Changhua and 1 other locations
- Changhua christian hospital — Changhua, Taiwan (RECRUITING)
- Changhua christian hospital — Changhua, Taiwan (RECRUITING)
Study contacts
- Principal investigator: Sen Yung Liu, MD — Changhua Christian Hospital
- Study coordinator: Sen Yung Liu, MD
- Email: 88925@cch.org.tw
- Phone: 88647238595
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Transcranial Magnetic Stimulation, Spinocerebellar Ataxias, rTMS, SCA