Using Rosemary and Daylily supplements to improve sleep quality in middle-aged adults
Effects of 8-week Supplementation With Two Doses of Rosemary and Daylily on Sleep Quality, Circadian Rhythms, Energy Metabolism, and Biochemical Indices in Middle-Aged Adults: A Randomized, Placebo-Controlled Crossover Trial.
This study is testing whether taking Rosemary and Daylily supplements can help middle-aged adults sleep better over eight weeks.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University of Novi Sad, Faculty of Sport and Physical Education Academic / other |
| Locations | 1 site (Novi Sad, Vojvodina) |
| Trial ID | NCT06859879 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of two different doses of Rosemary and Daylily herbal extracts on sleep quality and related health outcomes in middle-aged adults. Over an eight-week period, participants will receive either a low-dose, medium-dose, or placebo control of the supplements in a randomized, placebo-controlled, crossover design. The trial aims to assess improvements in sleep quality, circadian rhythms, energy metabolism, and relevant biochemical markers. Participants must meet specific eligibility criteria, including age and sleep difficulties.
Who should consider this trial
Good fit: Ideal candidates are middle-aged adults over 50 years old who experience trouble falling asleep more than five times a month.
Not a fit: Patients with a history of dietary supplement use within two weeks prior to the study or those with significant alcohol consumption may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a natural supplement option for improving sleep quality in middle-aged adults.
How similar studies have performed: While there is limited data on the specific combination of Rosemary and Daylily, herbal supplements have shown promise in improving sleep quality in other studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 50 years * Trouble falling asleep \> 5 times a month (NHANES criteria) * Body mass index 18.5-29.9 kg/m2 * Free of major chronic diseases or acute disorders * Given written informed consent Exclusion Criteria: * History of dietary supplement use \> 2 weeks before the study commences * Abnormal values for lab clinical chemistry (\> 2 SD) * Unwillingness to return for follow-up analysis * Participation in other clinical trials * Moderate-to-heavy use of alcohol (\> 3 drinks per week)
Where this trial is running
Novi Sad, Vojvodina
- Applied Bioenergetics Lab at Faculty of Sport and PE — Novi Sad, Vojvodina, Serbia (Recruiting)
Study contacts
- Study coordinator: Sergej M Ostojic, MD, PhD
- Email: sergej.ostojic@chess.edu.rs
- Phone: +38121450188
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.