Using rose scent to reduce breathing pauses during seizures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults admitted to the epilepsy monitoring unit will have 24 hours of routine EEG and respiratory monitoring followed by 24 hours of continuous rose scent exposure via an essential oil diffuser while monitoring continues. Participants will wear a respiratory belt across the upper chest throughout the 48-hour period to measure breathing and researchers will compare respiratory and EEG data between the baseline and scent-exposure periods. The protocol enrolls adults undergoing observational EEG monitoring without medication changes and does not introduce other seizure interventions. The study aims to identify whether olfactory exposure to rose odor alters the frequency or severity of ictal apnea events.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult epilepsy patients over the age of 18
* Admission to the inpatient epilepsy monitoring unit (EMU) at Vanderbilt University Medical Center (VUMC)
* Undergoing observational EEG monitoring without treatment involving seizure medication changes or other interventions for at least 48 hours

Exclusion Criteria:

* Patients under the age of 18
* Patients receiving EEG monitoring without interventions from baseline for less than 48 hours
* Patients who are not receiving EEG monitoring as a part of their inpatient admission.

Where it's running

• Vanderbilt University Medical Center
  Nashville, Tennessee, United States Recruiting

Study contacts

• Study coordinator: Brigitte Jia, BA
• Email: brigitte.jia@vanderbilt.edu
• Phone: 925-378-9234

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• RAP-219 long-acting injectable safety and PK study in healthy adults

  This early study tests RAP-219-LAI in healthy adults to see how it behaves in the body and whether it is safe and tolerable.

  Recruiting Phase 1 Rapport Therapeutics Inc. · Adelaide · NCT07923097

• Why People with Epilepsy Get More Infections

  This study tests whether anti-seizure medicines affect immune function and infection risk in people with epilepsy.

  Recruiting University of Aberdeen · Aberdeen · NCT07903168

• Long-Term Epilepsy Outcomes in Children After Perinatal Stroke

  This study looks at how epilepsy progresses in kids who had a stroke before 28 days old to see how their seizures and syndromes evolve over time.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07898397

• Hypothalamus structure and heart autonomic changes in drug-resistant epilepsy

  This study tests whether structural changes in the hypothalamus relate to cardiac autonomic dysfunction in adults with drug-resistant epilepsy.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens, Picardie · NCT07888543

• One-day exercise test to see how brain and body react in epilepsy, cognitive disorders, Parkinson's, dementia, and related conditions

  A one-day study tests how an acute bout of exercise changes brain function and bodily signals in people with certain neurological conditions compared with healthy individuals.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT07883720

• Advanced 7T fMRI for brain function in epilepsy and brain injuries

  This study tests ultra-high-field brain scans at 7T to see if they can better map brain function in adults with epilepsy or brain lesions and in healthy volunteers.

  Recruiting Imago 7 Fondazione di Ricerca onlus · Pisa, Italy · NCT07865546

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.