Using Ringer's Lactate to Prevent Low Blood Pressure After Anesthesia
Dose Responsive Study of Ringer's Lactate Solution in Prevention of Post-induction Hypotension Predicted by Inferior Vena Cava Collapsibility Index in Patients Receiving General Anesthesia
This study is testing whether giving different amounts of Ringer's Lactate solution before anesthesia can help prevent low blood pressure in patients during surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Tata Main Hospital Academic / other |
| Locations | 1 site (Jamshedpur, Jharkhand) |
| Trial ID | NCT05924230 on ClinicalTrials.gov |
What this trial studies
This study evaluates how different doses of Ringer's Lactate solution can prevent low blood pressure following the induction of general anesthesia. Patients will undergo an ultrasound to measure the diameter of the inferior vena cava to predict their risk of post-induction hypotension. Based on their body weight and assigned group, patients will receive either 10ml/kg or 15ml/kg of Ringer's Lactate before anesthesia induction. Continuous monitoring of vital signs will occur throughout the procedure to assess the effectiveness of the intervention.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 years and older undergoing elective surgery with ASA physical status classification I or II.
Not a fit: Patients under 18 or over 65 years, those with ASA classification III or IV, or those undergoing emergency surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of post-induction hypotension, improving patient safety during surgeries.
How similar studies have performed: While the specific approach of using Ringer's Lactate in this context may be novel, similar studies have shown that fluid preloading can help mitigate hypotension during anesthesia.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years American Society of Anesthesiologists (ASA) Physical status classification system group I and II Elective surgery under General anesthesia Exclusion Criteria: * Age \<18 and \> 65 American Society of Anesthesiologists (ASA) Physical status classification system group III and IV Systolic blood pressure ≥ 180 mmHg Systolic blood pressure \< 90 mmHg Pregnant women Patients with abdominal mass or ascites Emergency surgery
Where this trial is running
Jamshedpur, Jharkhand
- Abhishek Chatterjee — Jamshedpur, Jharkhand, India (Recruiting)
Study contacts
- Principal investigator: Abhishek Chatterjee — Tata Steel
- Study coordinator: Chatterjee
- Email: dr.abhishek@tatasteel.com
- Phone: +917763807075
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.