Using Rimegepant to treat migraine in real-world settings

A Prospective Real World Study of Rimegepant in the Treatment of Migraine

Observational Ruijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine · NCT05709106

This study is testing how well Rimegepant works for people with migraines in everyday life and if it's safe to use.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorRuijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine Academic / other
Locations1 site (Boao, Hainan)
Trial IDNCT05709106 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the effectiveness and safety of Rimegepant for treating migraine patients in real-world conditions. Participants will take Rimegepant as needed for migraine attacks and will record their experiences, including efficacy and any adverse events, at specified intervals. Additionally, they will track their monthly migraine days and complete patient-reported outcomes during follow-ups to assess long-term treatment effects.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older diagnosed with migraines who are prescribed Rimegepant.

Not a fit: Patients with severe cognitive impairments or those who are pregnant or lactating may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the real-world effectiveness of Rimegepant for migraine management.

How similar studies have performed: Other studies have shown promise in using Rimegepant for migraine treatment, but this specific observational approach is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects diagnosed as migraines (with or without aura) consistent with a diagnosis according to the International Classification of Headache Disorders, 3rd Edition, beta version
* Rimegepant is prescribed by the physician for the treatment of patients with migraine.
* Patients signed written informed consent.
* Male and Female subjects ≥ 18 years and older
* Patients is not participated in other concurrent interventional clinical studies.

Exclusion Criteria:

* The patients with severe visual, hearing, language, intelligence, memory, and consciousness disorders, are unable to cooperate with the completion of the questionnaire and follow-up.
* Pregnant patients
* Lactating female patients
* Patients who are highly dependent on medical care.

Where this trial is running

Boao, Hainan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Migraine
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.