Using Resveratrol Gel to Reduce Pain After Gum Surgery
Efficacy of Resveratrol-Based Gel Versus Hyaluronic Acid Gel as a Palatal Wound Dressing Materials on Postoperative Pain Following Free Gingival Graft Surgery: A Randomized Controlled Clinical Trial
This study is testing whether a Resveratrol gel can help reduce pain after gum surgery better than a Hyaluronic acid gel.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06521333 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effectiveness of a Resveratrol-based gel versus a 0.2% Hyaluronic acid gel applied to the palatal donor site following free gingival graft surgery. The approach involves a comprehensive periodontal treatment prior to surgery, followed by the harvesting of a free gingival graft from the palate. Post-operative pain management will be assessed by applying either gel or an acrylic resin stent alone to the surgical site. The goal is to determine which treatment option provides better pain relief after the procedure.
Who should consider this trial
Good fit: Ideal candidates are systemically healthy adults over 18 years old with mucogingival defects scheduled for free gingival graft surgery.
Not a fit: Patients who are pregnant, breastfeeding, smokers, or have allergies to the materials used will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing gum surgery.
How similar studies have performed: While there is limited data on the specific use of Resveratrol gel in this context, similar studies have shown promise in using alternative gels for post-operative pain management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patient over 18 years of age 2. Systemically healthy 3. Plaque index (PI) and gingival index (GI) less than 15% (Silness \& Löe) 4. Patients with Mucogingival defects scheduled for free gingival graft Exclusion Criteria: 1. Pregnancy or breastfeeding. 2. Occlusal trauma at site of graft. 3. Severe gagging reflex 4. Smokers. 5. Patients allergic to the used materials.
Where this trial is running
Cairo
- Faculty of dentistry, Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Principal investigator: Liza S ALhakam — master student.
- Study coordinator: Liza S ALhakam, BDS
- Email: liza.alhakam@dentistry.cu.edu.eg
- Phone: 01555325810
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.