Using Remifentanil to Reduce Emergence Agitation After Rhinoplasty
Efficacy of Remifentanil in Preventing Emergence Agitation in Patients Undergoing Nasal Surgery Under Desflurane Anesthesia: A Prospective Double-blind Randomized Controlled Trial.
NA · Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital · NCT06539013
This study is testing whether using remifentanil can help prevent agitation after nose surgery compared to other pain relief methods like fentanyl and nitrous oxide.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 99 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital (other) |
| Locations | 1 site (Diyarbakır, Kayapınar) |
| Trial ID | NCT06539013 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of remifentanil in preventing emergence agitation compared to fentanyl and nitrous oxide in patients undergoing rhinoplasty with desflurane anesthesia. It will assess various factors including demographic data, hemodynamic parameters, surgical duration, and recovery scores among the different analgesia methods used. The study will include adult patients classified as ASA I-II who are scheduled for the procedure. By comparing these analgesic approaches, the study seeks to identify the most effective method for minimizing postoperative agitation.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old scheduled for rhinoplasty and classified as ASA I-II.
Not a fit: Patients with ASA III or higher, those with a BMI over 35, or individuals with contraindications to general anesthesia will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved postoperative recovery experiences for patients undergoing rhinoplasty.
How similar studies have performed: Other studies have shown varying degrees of success with remifentanil in similar contexts, but this specific comparison is less commonly explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: The study included patients over the age of 18, planned to undergo rhinoplasty by the plastic and reconstructive surgery department, and American Society of Anesthesiologist (ASA) I-II. \- Exclusion Criteria: * Patients with a known history of allergy to the drugs to be administered in the study, ASA III and above, body mass index (BMI) 35\>kg/m2, younger than 18 years of age, any problems that would prevent general anesthesia in the preoperative evaluation (upper respiratory tract infection, etc.), and those who did not agree to participate in the study were excluded from the study.
Where this trial is running
Diyarbakır, Kayapınar
- Health Sciences University Gazi Yaşargil Training and Research Hospital — Diyarbakır, Kayapınar, Turkey (Türkiye) (RECRUITING)
Study contacts
- Study coordinator: Hülya Tosun Söner
- Email: hulyatosunsoner@hotmail.com
- Phone: +905352792102
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Emergence Agitation