Using Remifentanil and Remimazolam to Reduce Patient Movement During Long Eye Surgeries

Remifentanil and Remimazolam to Limit Patient Movement During Long-Eye Surgeries Under Local Anesthesia

Not applicable Interventional Egymedicalpedia · NCT06583811

This study is testing if using Remifentanil and Remimazolam can help keep patients calm and still during long eye surgeries while making them more comfortable.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment70 (estimated)
Ages40 Years to 50 Years
SexAll
SponsorEgymedicalpedia Industry-sponsored
Locations1 site (Cairo)
Trial IDNCT06583811 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the use of Remifentanil and Remimazolam as sedative agents to enhance patient comfort and minimize movement during long ophthalmic surgeries performed under local anesthesia. The study aims to evaluate the effectiveness of these medications in providing stable anesthesia while reducing side effects commonly associated with traditional anesthetics like propofol. By closely titrating the doses of these ultrashort-acting agents, the trial seeks to improve surgical outcomes and patient satisfaction. The study will include patients aged over 40 undergoing lengthy eye procedures, ensuring a controlled and safe environment for both patients and surgeons.

Who should consider this trial

Good fit: Ideal candidates for this study are patients over 40 years old, of both sexes, who are undergoing long-eye surgeries under local anesthesia.

Not a fit: Patients with conditions such as uncontrolled hypertension, severe liver or kidney dysfunction, or those on anticoagulants may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve patient comfort and safety during long eye surgeries.

How similar studies have performed: Other studies have shown promising results with similar sedative approaches, indicating potential for success in this novel application.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 40 years.
* Both sexes.
* American Society of Anesthesiology (ASA) physical status I-III.
* Undergoing long-eye surgeries under local anesthesia using peribulbar block with an expected surgical time of more than one hour.

Exclusion Criteria:

* Patients on aspirin or anticoagulants.
* Allergy to any study medication.
* Drug abuse.
* Uncontrolled hypertension.
* Hyperthyroidism.
* Frequent cough.
* Impaired hearing.
* Severe liver and kidney dysfunction.
* Neurological or psychological disorders.
* Partial or failed block.

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Long-Eye Surgeries
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.