Using red laser therapy to improve healing in palate wounds after gingival graft surgery

Photobiomodulation in Gingival Graft Donor Areas: Clinical, Somatosensory, and Quality of Life Evaluations

Not applicable Interventional University of Sao Paulo · NCT06073678

This study is testing if using red laser therapy can help people heal better and feel less pain after having gum surgery compared to just using regular wound dressings.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorUniversity of Sao Paulo Academic / other
Locations1 site (Bauru, São Paulo)
Trial IDNCT06073678 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effects of photobiomodulation using red laser on the healing of gingival graft donor areas in the palate compared to standard wound dressing protection. Participants requiring gingival graft surgeries will be randomly assigned to receive either laser treatment or just wound dressing. The study will assess the speed of somatosensory recovery, pain reduction, and overall quality of life improvements over a period of 60 days. Data collected will help determine the efficacy of laser therapy in enhancing recovery outcomes.

Who should consider this trial

Good fit: Ideal candidates are patients with healthy mucosa in the palate who are scheduled for gingival graft surgery.

Not a fit: Patients with prosthetic coverage of the palate, previous gingival graft removals, smokers, pregnant or breastfeeding women, and those on anticonvulsants or immunosuppressants may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to faster recovery and reduced pain for patients undergoing gingival graft surgeries.

How similar studies have performed: While the specific application of photobiomodulation in palate wounds is novel, similar studies have shown promising results in other surgical contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Palate with normal and healthy mucosa
* Patient with indication of gingival graft surgery

Exclusion Criteria:

* Patients using prosthesis with palate coverage
* Former removal of gingival graft in the palate
* Smokers
* Pregnancy and breastfeeding mothers
* Use of anticonvulsants and immunosuppressors

Where this trial is running

Bauru, São Paulo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Surgical Wound
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.