Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using Raman Spectroscopy to Diagnose Extrahepatic Cholangiocarcinoma

Official title: Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma

Run by University Hospital Olomouc · NCT06964425 · Data updated 2026-11-12

This study is testing a new way to diagnose extrahepatic cholangiocarcinoma using a special light technique during a procedure to see if it can better identify cancer in the bile ducts.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment20 (estimated)
SponsorUniversity Hospital Olomouc
Academic / other
Locations1 site (Olomouc, Olomouc Region)
StatusRecruiting
StartedFebruary 4, 2023
Main results expectedMay 31, 2025
Study endsJuly 30, 2025
Registry record updatedJuly 2, 2025
Trial IDNCT06964425 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years old who have a confirmed diagnosis of extrahepatic cholangiocarcinoma and require ERCP.

Probably not a fit

Patients who disagree with participation in the study will not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study aims to enhance the diagnosis of extrahepatic cholangiocarcinoma by utilizing Raman spectroscopy, an optical method that analyzes scattered light to create a molecular 'fingerprint' of tissues. During endoscopic retrograde cholangiopancreatography (ERCP), a fiber Raman probe is introduced into the bile ducts to collect data from both cancerous and healthy tissues. The study involves performing multiple Raman spectroscopy measurements to develop a reliable methodology for in vivo diagnostics. The data collected will be analyzed by a specialized biophysicist to improve diagnostic capabilities.

Why it matters

Potential benefit: If successful, this approach could significantly improve the accuracy of diagnosing extrahepatic cholangiocarcinoma, leading to better patient outcomes.

How similar studies have gone: While this approach is novel, similar studies using Raman spectroscopy for other diagnostic purposes have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* person older than 18 years, who has known extrahepatic cholangiocarcinoma and is indicated for ERCP

Exclusion Criteria:

* disagreement with the study

Where it's running

  • Peter Slodička
    Olomouc, Olomouc Region, Czechia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.