Using Raman Spectroscopy to Diagnose Extrahepatic Cholangiocarcinoma
Official title: Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma
Run by University Hospital Olomouc · NCT06964425 · Data updated 2026-11-12
This study is testing a new way to diagnose extrahepatic cholangiocarcinoma using a special light technique during a procedure to see if it can better identify cancer in the bile ducts.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | University Hospital Olomouc Academic / other |
| Locations | 1 site (Olomouc, Olomouc Region) |
| Status | Recruiting |
| Started | February 4, 2023 |
| Main results expected | May 31, 2025 |
| Study ends | July 30, 2025 |
| Registry record updated | July 2, 2025 |
| Trial ID | NCT06964425 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who have a confirmed diagnosis of extrahepatic cholangiocarcinoma and require ERCP.
✕Probably not a fit
Patients who disagree with participation in the study will not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study aims to enhance the diagnosis of extrahepatic cholangiocarcinoma by utilizing Raman spectroscopy, an optical method that analyzes scattered light to create a molecular 'fingerprint' of tissues. During endoscopic retrograde cholangiopancreatography (ERCP), a fiber Raman probe is introduced into the bile ducts to collect data from both cancerous and healthy tissues. The study involves performing multiple Raman spectroscopy measurements to develop a reliable methodology for in vivo diagnostics. The data collected will be analyzed by a specialized biophysicist to improve diagnostic capabilities.
Why it matters
Potential benefit: If successful, this approach could significantly improve the accuracy of diagnosing extrahepatic cholangiocarcinoma, leading to better patient outcomes.
How similar studies have gone: While this approach is novel, similar studies using Raman spectroscopy for other diagnostic purposes have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * person older than 18 years, who has known extrahepatic cholangiocarcinoma and is indicated for ERCP Exclusion Criteria: * disagreement with the study
Where it's running
-
Peter Slodička
Olomouc, Olomouc Region, Czechia Recruiting
Study contacts
- Principal investigator: Peter Slodička, M.D. — University Hospital Olomouc
- Study coordinator: Peter Slodička, M.D.
- Email: peter.slodicka@fnol.cz
- Phone: +420776807612
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.