Using pulsed radiofrequency and platelet-rich plasma to treat glossopharyngeal neuralgia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness and safety of combining pulsed radiofrequency (PRF) treatment with platelet-rich plasma (PRP) for patients suffering from idiopathic glossopharyngeal neuralgia (GPN). Participants must be over 18 years old and have previously failed pharmacotherapy or experienced intolerable side effects from medications. The study will monitor patients undergoing PRF treatment for GPN, with follow-up assessments conducted for at least one month to evaluate outcomes. The goal is to determine if this combined approach can provide better relief from symptoms compared to standard treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. age \>18 years;
2. diagnosed with idiopathic GPN according to the third International Classification of Headache Disorders (ICHD) classification;
3. patients who failed pharmacotherapy or intolerable side effects of medication;
4. undergoing PRF for GPN;
5. at least 1 month of follow-up recordings.

Exclusion Criteria:

1. Patients with bilateral GPN;
2. Abnormalities in blood measurements, liver and kidney function, blood glucose, coagulation, electrocardiography or chest radiography;
3. Infection at the puncture site;
4. Previous mental illness;
5. Previous history of narcotic drug abuse;
6. Prior anticoagulant or antiplatelet therapy;
7. An implantable pulse generator;
8. Current pregnancy or breast feeding.
9. Patients with incomplete medical records (lack of baseline data or postoperative follow-up data).

Where it's running

• Beijing Tiantan Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Fang Luo, M.D.
• Email: 13611326978@163.com
• Phone: +86 13611326978

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.