Using PTeye to identify parathyroid glands in patients with adenoma

Do PTeye Score Correlate With Biochemical Markers in Parathyroid Adenoma?

Observational Aristotle University Of Thessaloniki · NCT06913296

This study is testing if a special device called PTeye can help doctors find parathyroid glands more easily during surgery for patients with parathyroid adenoma.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorAristotle University Of Thessaloniki Academic / other
Locations1 site (Thessaloniki)
Trial IDNCT06913296 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the effectiveness of the PTeye autofluorescence device in identifying parathyroid glands during parathyroidectomy for patients with parathyroid adenoma. The study will correlate the device's performance with biochemical data from these patients to assess its utility in surgical settings. The research focuses on two approaches to near-infrared autofluorescence: camera-based systems and probe-based systems like PTeye. By analyzing the outcomes, the study seeks to enhance surgical precision and patient safety.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with primary hyperparathyroidism caused by adenoma.

Not a fit: Patients with secondary or tertiary hyperparathyroidism, those undergoing re-operation for adenoma, or individuals with previous neck surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of parathyroid gland identification during surgery, leading to better surgical outcomes for patients.

How similar studies have performed: While the use of near-infrared autofluorescence devices is gaining attention, this specific evaluation of the PTeye device's correlation with biochemical data is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>18 years old
* primary hyperparathyroidism caused by adenoma
* patient's informed consent acquired

Exclusion Criteria:

* Secondary and tertiary hyperparathyroidism
* Re-operation for adenoma
* Previous neck surgery
* Patient enrolled in another study that may affect the results of this study

Where this trial is running

Thessaloniki

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Parathyroid Adenomaparathyroid adenomanear-infrared autofluorescence
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.