Clinical trial No longer in our active list Phase2; Phase3 Interventional Ages 18 to 99

Using propofol for anesthesia in liver transplant surgery

Official title: Effect of Isoflurane and Target Control Infusion (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients: A Randomized Controlled Trial.

Run by Institute of Liver and Biliary Sciences, India · NCT06418893 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing whether using propofol instead of isoflurane for anesthesia during liver transplant surgery can lead to better heart and kidney function after the operation.

Quick facts

PhasePhase2; Phase3
Study typeInterventional
Ages18 Years to 99 Years
SexAll
Enrollment60 (estimated)
SponsorInstitute of Liver and Biliary Sciences, India
Academic / other
Locations1 site (Delhi)
Trial IDNCT06418893 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old who are scheduled for a living donor liver transplant.

Probably not a fit

Patients with acute liver failure, pre-existing cardiac or renal dysfunction, or allergies to propofol will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of target-controlled infusion (TCI) propofol compared to isoflurane on intraoperative hemodynamics and postoperative liver and kidney functions in patients undergoing living donor liver transplants. The research aims to determine whether propofol's antioxidant properties can provide better outcomes in terms of organ protection during surgery. By analyzing the hemodynamic stability and recovery profiles associated with each anesthetic agent, the study seeks to enhance patient care in liver transplant procedures.

Why it matters

Potential benefit: If successful, this study could lead to improved postoperative recovery and organ function in liver transplant recipients.

How similar studies have gone: While there is limited research directly comparing propofol and isoflurane in this specific context, the use of propofol has shown promise in other surgical settings, suggesting potential benefits.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:-Above 18 years of age who will undergo living donor liver transplant

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Exclusion Criteria: Refusal to consent

* Acute liver failure, Acute on chronic liver failure
* Allergic to propofol or any component of propofol
* Patients with pre existing cardiac dysfunction and cardiomyopathy
* Patients with pre existing renal dysfunction/ deranged RFTs preoperatively

Where it's running

  • Institute of liver and biliary sciences
    Delhi, India
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.