Using propofol for anesthesia in liver transplant surgery
Official title: Effect of Isoflurane and Target Control Infusion (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients: A Randomized Controlled Trial.
Run by Institute of Liver and Biliary Sciences, India · NCT06418893 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether using propofol instead of isoflurane for anesthesia during liver transplant surgery can lead to better heart and kidney function after the operation.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Institute of Liver and Biliary Sciences, India Academic / other |
| Locations | 1 site (Delhi) |
| Trial ID | NCT06418893 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who are scheduled for a living donor liver transplant.
✕Probably not a fit
Patients with acute liver failure, pre-existing cardiac or renal dysfunction, or allergies to propofol will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of target-controlled infusion (TCI) propofol compared to isoflurane on intraoperative hemodynamics and postoperative liver and kidney functions in patients undergoing living donor liver transplants. The research aims to determine whether propofol's antioxidant properties can provide better outcomes in terms of organ protection during surgery. By analyzing the hemodynamic stability and recovery profiles associated with each anesthetic agent, the study seeks to enhance patient care in liver transplant procedures.
Why it matters
Potential benefit: If successful, this study could lead to improved postoperative recovery and organ function in liver transplant recipients.
How similar studies have gone: While there is limited research directly comparing propofol and isoflurane in this specific context, the use of propofol has shown promise in other surgical settings, suggesting potential benefits.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria:-Above 18 years of age who will undergo living donor liver transplant - Exclusion Criteria: Refusal to consent * Acute liver failure, Acute on chronic liver failure * Allergic to propofol or any component of propofol * Patients with pre existing cardiac dysfunction and cardiomyopathy * Patients with pre existing renal dysfunction/ deranged RFTs preoperatively
Where it's running
-
Institute of liver and biliary sciences
Delhi, India Recruiting
Study contacts
- Study coordinator: Abhinav Sharma, MD
- Email: abhi27sh@gmail.com
- Phone: 8860790151
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.