Using probiotics to treat vaginitis
Official title: Evaluating the Effectiveness in Supportive Treatment of Vaginitis of Vaginal-spraying Bacillus Probiotic Spore Suspension (LiveSpo X-Secret)
Run by Anabio R&D · NCT06165354 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new vaginal spray probiotic to see if it can help women with vaginitis feel better without the side effects of antibiotics.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | Women only |
| Enrollment | 120 (estimated) |
| Sponsor | Anabio R&D Industry-sponsored |
| Locations | 2 sites (Ba Dinh, Hanoi and 1 other locations) |
| Trial ID | NCT06165354 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 18 to 60 who have been diagnosed with vaginitis and exhibit specific symptoms.
✕Probably not a fit
Patients who are pregnant, breastfeeding, or have certain medical conditions such as diabetes or cancer may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of LiveSpo X-SECRET, a vaginal spray probiotic containing Bacillus strains, on women diagnosed with vaginitis. The research aims to address the limitations of traditional antibiotic treatments, which can disrupt the natural balance of vaginal bacteria and lead to antibiotic resistance. By utilizing a targeted probiotic approach, the study seeks to improve symptoms associated with vaginitis, such as inflammation and discomfort. Participants will be women aged 18 to 60 who exhibit clear symptoms of vaginitis and test positive for specific pathogens.
Why it matters
Potential benefit: If successful, this treatment could provide a more effective and safer alternative to antibiotics for managing vaginitis.
How similar studies have gone: Previous studies have shown promising results with probiotic treatments for bacterial vaginosis, suggesting potential success for this novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women from 18 to 60 years old * Diagnosed with vaginitis with obvious symptoms and manifestations such as: vulvar/vaginal ulcers, inflammation, vaginal odor, vaginal itching, vaginal cololr, painful/ painful urination, lower abdominal pain; pain during sex; abnormal vaginal bleeding... * Positive for one of the following pathogents that cause vaginitis, such as Gardnerella vaginalis, Mycoplasma hominis, Candida albicans, Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, HSV-1, HSV-2, Trichomonas vaginalis, detected by real-time PCR assay. * The patient agrees to participate in the study, explains and signs the consent form to participate in the study. Exclusion Criteria: * Women who are pregnant or breast-feeding, have diabetes, are using antibiotics/anti-inflammatory drugs in the vaginal area within the previous 14 days * Vaginal bleeding of unknown cause or cancer * Have a history of drug allergy and hypersensitivity to any ingredient in probiotics or placebo * Leave the study before day 7 * Simultaneous participation in another clinical trial or use of probiotics for the gynecological tract within the past 14 days * Meets criteria for mental, cognitive, depressive or anxiety disorders * Do not agree to participate in the study
Where it's running
-
Hanoi Obstetrics and Gynecology Hospital
Ba Dinh, Hanoi, Vietnam Recruiting -
Centers for Disease Control and Prevention
Bac Ninh, Vietnam Recruiting
Study contacts
- Principal investigator: Chuong C Nguyen, MSc. MD — Hanoi Obstetrics and Gynecology Hospital
- Study coordinator: Chuong C Nguyen, MSc. MD
- Email: chuongnc2912@gmail.com
- Phone: (84) 091 3368526
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Vaginitis Diagnostic Algorithm Pilot Using Nanopath and Other Tests
This study tests a new Nanopath vaginal test to see if it correctly detects vaginitis-causing pathogens in up to 1,000 people with vaginitis symptoms.
-
Evaluating WXSH0102 for treating vulvovaginal candidiasis
This study is testing a new drug called WXSH0102 to see if it can effectively treat vulvovaginal candidiasis and comparing it to a standard treatment.
-
Evaluating vulvovaginitis effects on surgical outcomes after vulvar excision
This study is testing how common vulvovaginitis is in women having surgery for non-cancerous vulvar conditions and whether it affects their recovery.
-
Treatment for aerobic vaginitis using Baofukang vaginal suppository
This study tests if a new vaginal suppository can help women with aerobic vaginitis feel better, comparing two different treatment lengths of 7 days and 14 days.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.