Using prism adaptation to treat unilateral spatial neglect after brain injury
Neglect Treatment by Prism Adaptation in the Acute Phase
This study tests if using special glasses that shift vision can help people with brain injuries who have trouble noticing things on one side improve their everyday skills.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 32 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | University of Geneva, Switzerland Academic / other |
| Locations | 1 site (Geneva, Canton of Geneva) |
| Trial ID | NCT06078111 on ClinicalTrials.gov |
What this trial studies
This project investigates the effects of prism adaptation as an early rehabilitation technique for treating unilateral spatial neglect in patients who have recently suffered a brain injury. Participants will be assigned to either an experimental group receiving prism treatment or a control group receiving neutral prisms, with both groups engaging in visuo-motor activities. The study will assess the effectiveness of the treatment through cognitive, functional, and motor-related measures, with follow-up evaluations conducted three months later. The goal is to improve long-term functional outcomes for patients affected by this cognitive disorder.
Who should consider this trial
Good fit: Ideal candidates are individuals experiencing their first neurological event, such as a stroke or brain tumor surgery, who exhibit signs of unilateral spatial neglect.
Not a fit: Patients with previous neurological disorders or cognitive deficits may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance rehabilitation outcomes for patients suffering from unilateral spatial neglect.
How similar studies have performed: While the use of prism adaptation is a novel approach in this specific context, similar interventions have shown promise in other studies addressing spatial neglect.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * First neurological event, affecting the right hemisphere or the left hemisphere (stroke, brain tumour post-surgery); * Structural images of the brain lesion available (magnetic resonance or tomographic scans); * Good Normal (or corrected) visual acuity; * Presence of USN, as assessed by a standard neuropsychological evaluation. Exclusion Criteria: * Previous neurological disorder and/or current or previous psychiatric disease. * Presence or suspicion of previous general cognitive deficits documented from the clinical dossier and/or suspicious of possible cognitive deficits ; * Presence of difficulty in task's comprehension preventing its completion; * Impossibility to sustain a research session of at least 30 minutes (e.g., attentional lability).
Where this trial is running
Geneva, Canton of Geneva
- University Hospital of Geneva — Geneva, Canton of Geneva, Switzerland (Recruiting)
Study contacts
- Study coordinator: Roberta Ronchi, PhD
- Email: roberta.ronchi@hcuge.ch
- Phone: +41 (0)22 3728314
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.