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Clinical trial Recruiting at 1 site Interventional Ages 18 and up Men only

Using power Doppler ultrasound to improve needle localization during prostate brachytherapy

Official title: Needle Localization During Prostate Brachytherapy Using Power Doppler Ultrasound

Run by Western University, Canada · NCT03861507 · Data updated 2026-11-12

This study is testing whether using power Doppler ultrasound can help doctors place needles more accurately during prostate cancer treatment.

Quick facts

Study typeInterventional
Ages18 Years and up
SexMen only
Enrollment20 (estimated)
SponsorWestern University, Canada
Academic / other
Locations1 site (London, Ontario)
StatusRecruiting
StartedMarch 4, 2020
Main results expectedAugust 2025
Study endsDecember 2025
Registry record updatedMarch 28, 2025
Trial IDNCT03861507 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are males aged 18 years or older with pathologically confirmed prostate cancer who are suitable for high-dose-rate brachytherapy.

Probably not a fit

Patients who have previously received radiotherapy to the prostate may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on patients scheduled for standard brachytherapy treatment for prostate cancer. It aims to enhance the visualization of needle placement by utilizing power Doppler ultrasound in conjunction with a simple oscillator attached to the brachytherapy needle. The vibrations transmitted through the needle are expected to be captured by the ultrasound, providing better guidance during the procedure. This innovative approach seeks to improve the accuracy of needle localization compared to traditional 2D ultrasound methods.

Why it matters

Potential benefit: If successful, this method could lead to more precise brachytherapy treatments, potentially improving patient outcomes and reducing complications.

How similar studies have gone: While this approach is innovative, similar studies using advanced imaging techniques in brachytherapy have shown promise in improving treatment accuracy.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Male, aged 18 years or older
* Willing to provide written consent
* Pathologically confirmed prostate cancer on previous biopsy
* Suitable for and consenting to high-dose-rate brachytherapy for treatment as standard of care.

Exclusion Criteria:

* • Previous radiotherapy to the prostate

Where it's running

  • Victoria Hospital
    London, Ontario, Canada     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Prostate Cancer 1464Western University, Canada 26
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.