Using platelets rich plasma and PDO threads to treat stress incontinence in women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the efficacy and safety of combining platelets rich plasma (PRP) with PDO threads for treating stress urinary incontinence (SUI) in women aged 20 to 45. It will involve 10 women who have severe urodynamic stress incontinence and have previously failed conservative treatments. The intervention will be conducted at the Department of Obstetrics and Gynecology at Al-Azhar University in Cairo, Egypt. Participants will be monitored for improvements in their symptoms and overall quality of life following the treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Nonpregnant Women with SUI
* Age between 20 to 45 years
* Patients had a history of failed conservative treatment
* Patients were on the waiting list for surgical treatment of SUI

Exclusion Criteria:

* Under anti-platelet agent treatment
* Under NSAIDs
* Platelet dysfunction syndrome
* Critical thrombocytopenia
* Hypofibrionogenaemia
* Sepsis
* Acute and chronic infections
* Chronic liver disease
* Anti-coagulation therapy
* History of malignancy
* Pregnancy
* history of active malignant pathology
* mental disorders making them unable to give consent
* genitourinary fistula
* pelvic organs prolapse stage \>2 according to the Pelvic Organ Prolapse Quantification system, and detrusor overactivity on urodynamics.

Where it's running

• Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University.
  Cairo, Egypt Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.