Using Platelet Rich Plasma to Improve Recovery from Ankle Sprains
The Effect of Proprioception of Platelet Rich Plasma for Patients With Ankle Sprain
This study is testing if Platelet Rich Plasma injections, alone or with rehab therapy, can help people recover faster and better from severe ankle sprains.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | National Defense Medical Center, Taiwan Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT03808454 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of Platelet Rich Plasma (PRP) injections combined with rehabilitation therapy for patients suffering from second and third-degree ankle sprains. Participants will be randomly assigned to one of three groups: general rehabilitation therapy, PRP injection therapy, or a combination of both. The study aims to evaluate the impact of these treatments on proprioception and overall clinical function using a new ankle proprioception evaluation system. The goal is to establish a more effective and rapid treatment method for ankle sprains, enhancing recovery and coordination.
Who should consider this trial
Good fit: Ideal candidates are individuals with a recent ankle sprain (within one month) classified as second or third degree.
Not a fit: Patients with certain medical conditions such as cancer, liver cirrhosis, or those on anticoagulation therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce recovery time and improve functional outcomes for patients with ankle sprains.
How similar studies have performed: Other studies have shown promising results with PRP therapy in similar contexts, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ankle sprain within one months * Gr II or Gr III ankle sprain (anterior talus fibular ligament)by sonogram proved * MMSE≥23 * could cooperate the examination of the test Exclusion Criteria: * Hemianopsia or hemineglect any brain lesion such as cerebrum of cerebellum involved movement * cancer victim * pregnant If needed PRP treatment * Liver cirrhosis * Platelet \< 150000/UL * Sepsis, Leukemia * use anti-coagulation agents * under hemodialysis
Where this trial is running
Taipei
- Tri-service General Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Shang-Lin Chiang, PhD
- Email: andyyy520@yahoo.com.tw
- Phone: 8860287923311
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.