Using photo-medicine to guide reoperation for lymph nodes in recurrent breast cancer
Photo-medicine-Guided Dual Approach for Reoperation of Sentinel Lymph Nodes in Locally Recurrent Breast Cancer Patients
This study is testing a new method using light to help doctors find lymph nodes during surgery for women with recurrent breast cancer to see if it improves treatment planning.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | National Cancer Center, Korea Government |
| Locations | 1 site (Goyang-si) |
| Trial ID | NCT06780748 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates a dual approach using photo-medicine to guide the reoperation of sentinel lymph nodes in patients with locally recurrent breast cancer. The study aims to improve the identification rate of sentinel lymph nodes, which is crucial for effective staging and treatment planning. Participants will include female patients aged 18 and older who have previously undergone axillary surgery for breast cancer. The trial seeks to clarify the role of sentinel lymph node biopsy in the surgical management of recurrent cases, which remains uncertain according to current guidelines.
Who should consider this trial
Good fit: Ideal candidates are female patients aged 18 or older with ipsilateral locally recurrent breast cancer who have previously undergone axillary surgery.
Not a fit: Patients with distant metastases or those who have undergone ipsilateral mastectomy will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance surgical outcomes and reduce complications for patients with recurrent breast cancer.
How similar studies have performed: Recent studies have shown promising outcomes for repeat sentinel lymph node biopsy, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with ipsilateral locally recurrent breast cancer who previously underwent ipsilateral axillary surgery. * Female patients aged 18 years or older. * Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1. * Patients who voluntarily decide to participate in the study and provide written informed consent. Exclusion Criteria: * Patients with distant metastases. * Patients who previously underwent ipsilateral mastectomy. * Pregnant or breastfeeding women. * Patients with a general condition that impairs the ability to understand or provide informed consent.
Where this trial is running
Goyang-si
- National Cancer Center — Goyang-si, South Korea (Recruiting)
Study contacts
- Principal investigator: Seeyoun Lee — National Cancer Center, Korea
- Study coordinator: Seeyoun Lee
- Phone: +82-31-920-1736
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.