Using phenylephrine to reduce blood loss during burn surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the use of phenylephrine as an alternative to epinephrine for controlling blood loss during skin grafting in burn injuries. The study aims to determine if phenylephrine can effectively reduce blood loss without causing adverse effects on heart rate or blood pressure. Participants will receive injections of phenylephrine under the skin at the site of injury before undergoing standard surgical procedures. The goal is to evaluate the safety and efficacy of phenylephrine in this context.

Why it matters

Who can join: the full rules

Inclusion Criteria

a) Burn injury requiring debridement and grafting between 5-30% TBSA

Exclusion Criteria

1. Head and neck, hand, foot, or genital burns
2. On anticoagulants (except NSAIDs)
3. On monoamine oxidase inhibitor or tricyclic antidepressant
4. Coronary or peripheral vascular disease
5. History of arrhythmias
6. On a Beta-blocker
7. History of vascular abnormality
8. Hypertension

Where it's running

• University of Manitoba
  Winnipeg, Manitoba, Canada Recruiting

Study contacts

• Study coordinator: Justin Gawaziuk, MSc
• Email: jgawaziuk@hsc.mb.ca
• Phone: 2047873669

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.