Using phenylephrine to prevent low blood pressure during cesarean sections under spinal anesthesia
Tachycardia as an Indication for Prophylactic Phenylephrine Injection in Caesarean Section Under Spinal Anesthesia; an Observational Study
This study is testing if giving phenylephrine can help prevent low blood pressure in pregnant women having a cesarean section under spinal anesthesia when their heart rate is high.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 35 Years |
| Sex | Female |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Heliopolis) |
| Trial ID | NCT06220942 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of phenylephrine administration in preventing hypotension in women undergoing elective cesarean sections under spinal anesthesia when they experience tachycardia. Conducted at Ain Shams University Maternity hospitals in Cairo, Egypt, the study will involve 80 ASA II pregnant females aged 18-35 who provide informed consent. The methodology includes monitoring patients during the procedure and administering phenylephrine as needed based on their heart rate. Preoperative assessments will ensure patient safety and eligibility.
Who should consider this trial
Good fit: Ideal candidates are ASA II pregnant females aged 18-35 scheduled for elective cesarean sections.
Not a fit: Patients undergoing emergency or complicated cesarean sections, or those with ASA III or higher classifications and cardiovascular diseases, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of hypotension during cesarean sections, improving maternal safety and outcomes.
How similar studies have performed: Previous studies have indicated that phenylephrine can be effective in managing hypotension during spinal anesthesia, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA II pregnant female planned for elective C.S., aged between 18 -35 years old. Exclusion Criteria: * Emergency CS, Complicated CS (Severe bleeding, organ injury, uterine atony), ASA III, VI patients with cardiovascular diseases
Where this trial is running
Cairo, Heliopolis
- maha sadek El Derh — Cairo, Heliopolis, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.