Using phenazopyridine to reduce pain after urodynamic testing

Effectiveness of Phenazopyridine for Pain Following Urodynamics

PHASE4 · University of South Florida · NCT06577493

This study is testing if a medication called phenazopyridine can help reduce pain for adults after they have urodynamic testing.

Quick facts

PhasePHASE4
Study typeInterventional
Enrollment66 (estimated)
Ages18 Years to 99 Years
SexFemale
SponsorUniversity of South Florida (other)
Locations1 site (Tampa, Florida)
Trial IDNCT06577493 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of phenazopyridine, a medication commonly used to relieve urinary pain, in reducing discomfort experienced by patients following urodynamic testing. Participants will receive phenazopyridine at the time of their urodynamic study and will be assessed for pain levels using a visual analog scale. The study focuses on adult patients who require urodynamic testing and can provide informed consent. By comparing pain levels before and after the intervention, the study seeks to determine if phenazopyridine can significantly alleviate post-procedural pain.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who require urodynamic testing and can communicate in English or Spanish.

Not a fit: Patients with allergies to phenazopyridine or those with certain medical conditions such as severe renal insufficiency or interstitial cystitis may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide effective pain relief for patients undergoing urodynamic testing.

How similar studies have performed: While the specific use of phenazopyridine for this purpose may be novel, similar studies have explored pain management in urodynamic testing with varying degrees of success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ability to provide informed consent
* ability to complete visual analog scale
* requiring urodynamic testing
* 18 years of age or older
* must be able to read and write in English or Spanish

Exclusion Criteria:

* allergy to phenazopyridine
* a urinary tract infection in the prior 2 weeks
* women who did not undergo urodynamic testing
* patient less than 18 years old
* patients with known (noted in patient chart and verbally asked) severe renal insufficiency with GFR \<50 mL/min,
* patients with known (noted in patient chart and verbally asked) severe hepatitis
* patients with known (noted in patient chart and verbally asked) G6PD deficiency
* history of fibromyalgia
* history of interstitial cystitis
* non English or Spanish speaking

Where this trial is running

Tampa, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Pain After Urodynamic Testing

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.