Using PET/CT imaging to evaluate estrogen receptors in breast cancer
Official title: Estrogen Receptor (ER) PET/CT Imaging in Breast Cancer
Run by Tongji Hospital · NCT05541367 · Data updated 2026-11-12
This study is testing a special type of imaging to see how well it can measure estrogen receptors in patients with breast cancer to help improve their treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Tongji Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Wuhan, Hubei) |
| Status | Recruiting |
| Started | December 31, 2021 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | September 15, 2022 |
| Trial ID | NCT05541367 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old with pathologically confirmed breast cancer.
✕Probably not a fit
Patients who are pregnant or have severe underlying diseases that prevent cooperation with PET examination may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the efficacy of 18F-Fluoroestradiol (18F-FES) PET/CT imaging in evaluating estrogen receptor (ER) expression levels in patients with primary and metastatic breast cancer. The study focuses on understanding the heterogeneity of estrogen receptors and their role in treatment response and pharmacokinetics of estrogen receptor-targeted therapies. By utilizing a highly sensitive and specific imaging tracer, the study seeks to provide insights into the biological characteristics of breast cancer and improve treatment strategies for patients. Participants will undergo PET/CT scans to measure ER levels, contributing to a better understanding of breast cancer pathology.
Why it matters
Potential benefit: If successful, this study could enhance personalized treatment approaches for breast cancer patients by providing better insights into estrogen receptor status.
How similar studies have gone: Other studies utilizing PET imaging for evaluating estrogen receptors in breast cancer have shown promising results, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * More than 18 years old * Patients with pathologically confirmed breast cancer * Sign the informed consent form Exclusion Criteria: * Pregnant women * Severe underlying diseases that cannot cooperate with PET examination
Where it's running
-
TongjiHospital
Wuhan, Hubei, China Recruiting
Study contacts
- Principal investigator: Zhu Xiaohua, Dr — Tongji Hospital
- Study coordinator: Zhu Xiaohua, Dr
- Email: evazhu@vip.sina.com
- Phone: 13971513770
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.