Using PET imaging to evaluate HER2 expression in breast cancer patients after neoadjuvant therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the predictive and prognostic value of F-18 labeled HER2 Affibody PET imaging in patients with breast cancer who have received neoadjuvant therapy. By evaluating HER2 expression through advanced imaging techniques, the study seeks to provide insights into treatment responses and outcomes. The approach involves administering a molecular PET radionuclide to visualize HER2 expression levels in tumors, which may help tailor future treatment strategies for patients. The study is conducted at Peking University Cancer Hospital & Institute and involves collaboration with other medical institutions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged ≥18 years old; ECOG 0 or 1;
2. Patients with HER2 positive or low tumors;
3. Receives neoadjuvant therapy
4. Has adequate cardiac, bone marrow, renal, hepatic and blood clotting functions;
5. Life expectancy \> 3 months -

Exclusion Criteria:

1. Significant hepatic or renal dysfunction;
2. Is pregnant or ready to pregnant;
3. Cannot keep their states for half an hour;
4. Refused to join the clinical research;
5. Suffering from claustrophobia or other mental disorders;
6. Any other situation that researchers considered it unsuitable to participate in the trial.

Where it's running

• Peking University Cancer Hospital & Institute
  Beijing, China Recruiting

Study contacts

• Study coordinator: Xiaoyi Guo, PhD
• Email: 15833916752@163.com
• Phone: 010-88196495

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.