Using PET imaging to define esophageal cancer boundaries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of endosonography, mpMRI, and PET/CT imaging in accurately determining the boundaries of esophageal tumors before and after neoadjuvant therapy and surgery. It aims to improve the precision of tumor delineation, which is crucial for effective treatment planning in patients with esophageal cancer. By enhancing the accuracy of tumor boundary identification, the study seeks to minimize the risk of cancer recurrence and improve surgical outcomes. The trial is conducted at the University Hospital Heidelberg in Germany, focusing on patients with specific types of esophageal cancer.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Histologically confirmed adenocarcinoma or squamous cell carcinoma of the esophagus, including AEG I and AEG II tumors in the primary situation
* Planned surgical treatment of esophageal carcinoma
* Possible staging advantage through FAPI PET/CT diagnostics
* Patient information and written consent

  -\> KI 60% or ECOG 0/1 (at least: self-sufficiency)
* Age ≥ 18 years

Exclusion Criteria:

* Previous radiation therapy in the tumor region
* Previous tumor disease with \< 5 years of remission
* Surgical therapy is not functionally or technically possible
* Distant metastasis
* Patient is not capable of giving consent
* Concurrent participation in another clinical trial that could affect the results of this trial or the other trial
* Illnesses that do not allow the person concerned to assess the nature and scope as well as possible consequences of the clinical study
* pregnant or breastfeeding women
* Signs that the person taking part is unlikely to comply with the therapy (e.g. unwillingness to cooperate)

Where it's running

• Department of Radiotherapy, University of Heidelberg
  Heidelberg, Germany Recruiting

Study contacts

• Study coordinator: Christoph Fink, MD
• Email: christoph.find.@med.uni-heidelberg.de
• Phone: +496221 56

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.