Using Perfusion Index to Improve CPR Quality
Evaluation of Peripheral Pulse-oximeter Derived Perfusion Index as a Prognostication Tool for High Quality Cardiopulmonary Resuscitation and Return of Spontaneous Circulation
This study is testing if using a special tool to measure blood flow during CPR can help improve the chances of patients recovering after a cardiac arrest in the hospital.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 47 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | National Hepatology & Tropical Medicine Research Institute Government |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06067464 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the use of the perfusion index as a real-time feedback tool during cardiopulmonary resuscitation (CPR) to enhance its quality. It involves monitoring patients who experience in-hospital cardiac arrest, collecting demographic data, and recording vital signs such as end-tidal carbon dioxide (ETCO2) and pulse oximetry-derived perfusion index every minute during CPR. The goal is to determine if these measurements can help predict return of spontaneous circulation (ROSC) and improve patient outcomes. The study follows established advanced life support algorithms and tracks survival rates at one week and 30 days post-resuscitation.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 75 who have suffered an in-hospital cardiac arrest and received CPR for at least 3 minutes.
Not a fit: Patients who are pregnant, have known peripheral vascular disease, or are on more than two vasopressors may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved CPR techniques and better survival rates for patients experiencing cardiac arrest.
How similar studies have performed: While the use of ETCO2 and other monitoring tools in CPR has been explored, the specific application of perfusion index as a prognostication tool is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The subjects are adults aged between 18 \& 75years who developed in-hospital cardiac arrest and cardiopulmonary resuscitation for at least 3 minutes either in emergency departments or wards or Intensive care units in the National Hepatology and Tropical Medicine Research Institute (NHTMRI) and Alexandria University Exclusion Criteria: * Patients will be excluded from the study ifpregnant,known peripheral vascular disease or \>2 vasopressors with the maximum doses or in the presence of nail polish as readings from pulse oximeter will be distorted .
Where this trial is running
Cairo
- Nhtmri — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Eman Ibrahim El-Desoki Mahmoud, MD
- Email: eman18350@gmail.com
- Phone: +201227409501
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.