Using peppermint oil to lower blood pressure in people with mild to moderate hypertension

Effects of Peppermint Oil in Cardiometabolic Outcomes in Participants With Mild-moderate Hypertension.

Not applicable Interventional University of Central Lancashire · NCT05561543

This study is testing if taking peppermint oil can help lower blood pressure in adults with mild to moderate hypertension who aren't on medication.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversity of Central Lancashire Academic / other
Locations1 site (Preston, Lancashire)
Trial IDNCT05561543 on ClinicalTrials.gov

What this trial studies

This investigation aims to evaluate the effects of oral peppermint oil supplementation on cardiometabolic parameters in individuals with mild to moderate hypertension. The study will involve a placebo-controlled, randomized design to assess the impact of peppermint oil on systolic blood pressure and other cardiovascular metrics. Participants aged 18 to 65 with specific blood pressure readings will be recruited, and those not on blood pressure medications will be included. The study seeks to provide a dietary intervention alternative to traditional pharmacological treatments for hypertension.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-65 with systolic blood pressure between 120 to 139 mmHg who are not currently taking blood pressure medications.

Not a fit: Patients with diabetes, coronary heart disease, or those who are pregnant or lactating may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could offer a natural and low-risk dietary intervention for managing mild to moderate hypertension.

How similar studies have performed: Previous studies have shown positive effects of peppermint on blood pressure in healthy individuals, but this specific approach in hypertensive patients is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Aged from 18-65 years
2. Systolic blood pressure 120 to 139 mmHg
3. Not taking prescribed medicine for blood pressure management
4. have the ability to complete written questionnaires independently
5. Able to provide informed consent

Exclusion Criteria:

1. Diagnosed with diabetes mellitus and/ or coronary heart disease
2. Pregnant and lactating women
3. Allergy to peppermint
4. Habitual consumption of peppermint products
5. Regular consumption of antioxidant supplements

(5) Body mass index larger than 40.0 kg/m2 (6) Current enrolment in other clinical trials of other external therapies

Where this trial is running

Preston, Lancashire

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypertension
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.