Using PENS for pain relief after surgery in cancer patients
Official title: Efficacy of Percutaneous Electrical Neurostimulation (PENS)of the Auricle as an Opioid Sparing Postoperative Analgesic Technique in Cancer Endometrium and Cancer Cervix
Run by DyAnsys, Inc. · NCT05742711 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing if a device that uses tiny needles behind the ear can help relieve pain after surgery for cancer patients while reducing the need for opioids.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 48 (estimated) |
| Sponsor | DyAnsys, Inc. Industry-sponsored |
| Locations | 1 site (Chennai, Tamil Nadu) |
| Trial ID | NCT05742711 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 diagnosed with stage I or II cancer of the endometrium or cervix who are scheduled for elective surgery.
✕Probably not a fit
Patients with advanced cancer stages, emergency surgeries, or those with a history of opioid dependence or chronic pain may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study investigates the efficacy of percutaneous electrical nerve stimulation (PENS) as a postoperative analgesic technique for patients undergoing surgery for cancer of the endometrium and cervix. The study aims to provide effective pain relief while minimizing the use of opioids and their associated side effects. Participants will receive PENS treatment, which involves the application of a device with tiny needles behind the ear to stimulate nerves and alter pain perception. The study is double-blinded to ensure unbiased results and will compare the PENS treatment to a sham device.
Why it matters
Potential benefit: If successful, this approach could significantly reduce opioid use and its side effects in postoperative cancer patients.
How similar studies have gone: While the use of PENS is a novel approach in this context, similar techniques have shown promise in other pain management studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18 yrs * Diagnosed with CA-endometrium OR CA -cervix of stage I/II and post RT CA cervix patients coming for hysterectomy * Elective surgery * Informed consent obtained * ASA (American Society of Anaesthesiology) physical status 1-3 Exclusion Criteria: * Patient refusal * Cancer cervix other than the stages mentioned in inclusion criteria ASA PS \>3 * Emergency surgery, Laparoscopic and robotic procedures * Unplanned postoperative ventilation * Allergy/sensitivity to adhesive * Active skin infection/lesion in the ear region * H/O of seizure or cerebral disease * H/O chronic pain and prolonged analgesic usage * H/O opioid dependence * H/O anxiety or psychiatric illness requiring treatment * Pre-existing implantable/ electronic on demand device * Patients who might require MRI in the study period * Patients with transmissible diseases * Patients with coagulopathies * Absolute or relative contraindication to drugs used in the study
Where it's running
-
Cancer Institute,(Wia)
Chennai, Tamil Nadu, India Recruiting
Study contacts
- Principal investigator: Dr. Sahithya Sriman, MBBS, MD — Cancer Institue, WIA,
- Study coordinator: Dr. Sahithya Sriman
- Email: sahithyaadhithyan@gmail.com
- Phone: +91-9840226923
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.